Detection of iMLS B resistance among MRSA helps to avoid treatment failure with clindamycin. Studying the subpopulation inside the clindamycin-sensitive zone raises the question of existence of hetero-resistance or some other mechanism, which needs further study.
Medication errors can cause serious adverse effects and potentially to evoke the fatal risk of the disease. Monitoring the safety and efficacy of the drug adequately can prevent the occurrence of adverse effect. The main aim of this study is to identify and intervene the prescribing and dispensing errors among the Outpatient General Medicine department. Across sectional interventional study was carried out at the General Medicine Out-patient Department. The patients who satisfied inclusion and exclusion criteria were enrolled after obtaining their consent. The required data was collected in the patient's prescription and different types of medication errors was identified and documented. During this study period we found 303 prescriptions with medication errors out of 544 prescriptions. Of the 303 prescriptions prescribing errors was 315(79%) and 85(21%) were dispensing errors. The most common type of medication error was prescribing error. It was absence of strength (35.9%), absence of dosage regimen (32.4%), wrong drug (79.8%). The most common type of dispensing error was required quantity not supplied (55.7%), dispensing wrong drug (32.8%). Occurrence of medication errors was common in Outpatient General Medicine Department in this tertiary care teaching hospital. A clinical pharmacist can play a major role in early detection and prevention of medication errors and thus can improve the quality of care to the patients. Educating the patients about the drugs and their importance of right use can be helpful in minimizing errors.
Introduction and Objectives: CABG is the treatment of choice for severe left main coronary artery stenosis. The results of a number of multicenter trials have suggested angioplasty with stenting as a possible alternative treatment. Previous studies demonstrated procedural success of 90-100% and Mortality 0.8-2% So, want to see these parameters in Asian population though the LMCA registry of a referral center institute.Material and Methods: We have collected data from patient records who underwent LMCA angioplasty procedure (both unprotected or protected LMCA) performed at our institution between April 2003 to July 2015. Detailed in-hospital data including age, gender, coronary risk factors, procedural events were obtained and analyzed.Results: Angiographically documented success was obtained in 98% patients with zero mortality. In 134 patients the lesions were pre-dilated using a conventional balloon. In 19 patients direct stenting was done. The median diameter and length of the stent was 3.2542 mm and 13.790 mm, respectively. POBA was done in two cases, BMS were used in 27 cases, DES were used in 124 cases.Only LMCA stenting was done in 53 cases LMCA with other vessels stenting was done in 98 cases. FFR was used in 2 cases, Kissing balloon dilatation was used in 8 cases, ostial flaring was done in 5 cases. There was no mortality in the study but on table stent thrombosis was seen in one patient for which thrombuster was used, IABP was placed immediately and sent for CABG. For one case result was suboptimal.Conclusions: Present study demonstrated that stenting for significant LMCA disease is safe and feasible with very high procedural and clinical success rates and zero mortality. LMCA-left main coronary artery, POBA-plain old balloon angioplasty, PCI-Percutaneous coronary intervention, CABG-coronary artery bypass grafting, FFR-Fractional flow reserve, TIMI- thrombolysis in myocardial infarction, DES-drug eluting stent, BMS-bare metal stent, TLR-Target lesion revascularization.
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