INTRODUCTIONHypertensive pregnancy disorders complicate 10% of all pregnancies.1 WHO estimates that at least one woman dies every seven minutes from complications of hypertensive disorders during pregnancy. 2 The incidence of PIH is high among the women who have conceived for the 1st time.3 Preeclampsia (PE) is currently classified as a pregnancy-specific syndrome characterized by the presence of new-onset hypertension in a previously normotensive woman after 20 weeks of gestation with proteinuria. Eclampsia is classified as presence of seizures, non-attributable to other causes, in women diagnosed with PE. 4 If undetected, preeclampsia can lead to eclampsia which is one of the top five causes of maternal illness, infant illness and death. The risk of developing pre-eclampsia appears to be greater in women who have family histories of essential hypertension. 5Maternal endothelial dysfunction is considered as a classic hallmark of preeclampsia.6 Previous studies had stated that preeclamptic women had presented arterial ABSTRACT Background: Pregnancy induced hypertension is considered as the major cause of maternal and perinatal mortality. Even though occurrence of PIH is due to abnormal placentation, endothelial dysfunction plays a pivotal role in the genesis of the multisystem disorder that develops in pre eclampsia and eclampsia. Various studies have proved that hyperlipidemia is one of the major causes of endothelial dysfunction. Since ApoB/apoA-I ratio is a dyslipidemic indicator, the study was designed to determine ApoB/ApoA-I in PIH women and to analyse whether this ratio can be correlated with ED in PIH women. Methods: A cross-sectional analytical study involved normotensive, preeclamptic and eclamptic pregnant women with hundred subjects in each group. They were investigated for serum lipid profile, ApoA, ApoB, NO, MDA, FRAP in the 3rd trimester of pregnancy.

A 17-year-old short-statured girl (figure 1) presented with seizures, progressive cataracts, and tetany. Further evaluation revealed positive Chvostek sign (video), cerebrostriothalamic calcifications or Fahr syndrome, persistent hypocalcemia (total serum calcium 6.5 [normal 9 -10.5] mg/100 mL), and primary hypoparathyroidism (serum parathyroid hormone Ͻ3.0 [normal 12-72] pg/mL).Chvostek sign, seen in hypocalcemia, hypomagnesemia, or alkalosis, is also reported in children with epilepsy. 1 Calcifications in Fahr syndrome (figure 2) are distinguishable from those of physiologic and other causes, including hyperparathyroidism; phacomatoses; gliosis from CNS infections, trauma, or strokes; and neoplasms. Clinically, Fahr syndrome can be associated with rigidity, seizures, psychosis, and dementia. Short stature and primary hypoparathyroidism prompted investigations for a mitochondrial disorder, 2 but a muscle biopsy was normal.