An increase in the Caesarean Section (CS) rates is a concern in the health care systems all over the world. In a developing country, an increase in the CS rate has major implications on the limited health care resources. A hospital based retrospective study was carried out in a tertiary government-run hospital specializing in Obstetrics & Gynaecology & all deliveries conducted from Jan 1 st 2009 to Dec 31 st 2009 were included. There were 7543 deliveries in the study period, with 1756 being CS, giving a rate of 23.27%. There is an increasing trend of caesarean section from 2005 (20.24%) to 2009 (23.27%) in our hospital. Most of the CSs were performed with previous CS as the indication. Foetal distress, breech presentation and failed induction was the other non-absolute indications. Placenta praevia and malpresentations were the most common absolute indications of CS.

Edible oils are the essential part of diet, however, deep frying process induce oxidative changes in these oils, making them unsuitable for consumption. Deep frying generates various noxious polar and non-polar aldehydes and carbonyls, which may be polar or non-polar in nature. The present study thus evaluated the cytotoxic and hemolytic effects of polar and non-polar fractions of different deep fried edible oils. There observed a significantly elevated level of lipid peroxidation products in the polar fraction of deep fried sunflower (FSO-P) and rice bran oils (FRO-P). The treatment with these fractions induced cytotoxicity in cultured colon epithelial cells, with a higher intensity in FSO-P and FRO-P. Further, an increased TBARS level and catalase activity in RBCs treated with FSO-P and FRO-P led to hemolysis. In comparison, the fried coconut oil (FCO) fractions were less toxic and hemolytic; in addition, the non-polar fraction was more toxic, compared to FCO-P fraction.

Introduction Cardiac disease in pregnancy is a major problem worldwide, particularly in developing countries. It often poses a difficult clinical scenario with the responsibility of the treating obstetrician also extending to the unborn fetus. In the present study, we aim to know the maternal and fetal outcomes in pregnancies complicated by cardiac disease. Materials and methods All pregnant patients with cardiac disease who delivered at our institution during 2014 to 2016 were evaluated to look for the final pregnancy outcomes. Results Out of 36 study cases, 44.44% had no maternal complications, while 88.89% had good fetal/neonatal outcome. The commonest maternal cardiac complication was sustained tachyarrhythmia/bradycardia followed by pulmonary edema, while intrauterine growth restriction was encountered in fetal outcome. Conclusion Multidisciplinary team management of cardiac disease, led by an experienced obstetrician and cardiologist, reduces the adverse outcomes in pregnancies complicated by cardiac diseases. How to cite this article Sneha P, Sarojamma C, Nagarathnamma R. Cardiac Disease complicating Pregnancy: A Tertiary Care Center Experience. J Med Sci 2017;3(2):41-44.

Introduction: Congenital heart disease (CHD) if diagnosed clinically early and confirmed by ChestX-ray and ECHO, can be appropriately managed. Objectives: To observe the clinical profile of CHDin clinically diagnosed CHD in children To correlate the clinical profile with radiological andechocardiographic findings in the study group. Methods: It’s a cross-sectional study. The durationwas 18 months. All children in the age group of 1 month to 18years of age with history & clinicalfindings suggestive of CHDs were taken, assessed, subjected to Chest X-ray & 2 DECHO & werecorrelate. Results: Total no. of cases admitted during the study period was 5423, 624 had CHDamong which 50 fulfilling the criteria were taken. Clinically CCHD was in 34%, ACHD in 66%. Clinicalcorrelation with X-ray was 83% and with ECHO was 87 %. Conclusion: ACHD is more common,Chest x-ray findings correlated closely. ECHO correlation with the clinical diagnosis was veryaccurate especially in isolated lesions and some cases were identified which had been missedclinically. Hence Clinical Diagnosis with X-ray and ECHO helps in increased identification & earlierintervention of CHDs.

Multidrug resistance isolates of Acinetobacter sp. are increasing due to indiscriminate use of antibiotics in health care settings. The incidence of resistance to broad spectrum antibiotics is increasing and thus posing a therapeutic challenge. All samples were processed and isolates were identified as per standard protocol. 5Antibiotic susceptibility of all isolates was determined by the standard Kirby Bauer disc diffusion method as per Clinical laboratory standards institute (CLSI) guidelines 2017.6 Majority of the Acinetobacter sp. were isolated from E.T aspirates (47.3%). In our study A.baumannii (65.3%) was the most common species responsible for the infections. Among 150 Acinetobacter isolates, 68% of isolates were multidrug resistant organisms, 52% were extended spectrum beta-lactamase (ESBL) producers and 44% of isolates were carbapenem resistant. To abate antimicrobial resistance, antimicrobials ought to be prescribed sensibly and observational antimicrobial treatment ought to be resolved for every hospital as per institutional antibiogram. Strict adherence to the antibiotic policy and proper implementation of antibiotic stewardship program in coordination with clinicians can reduce emergence of multidrug resistant Acinetobacter species which is of great concern.