The NACS had poor reliability both on simultaneous testing and in the test-retest situation when used to evaluate term, healthy neonates. The authors suggest that other measures need to be developed to evaluate the effect of intrapartum drug administration in the neonate. Health measurement scales should undergo rigorous assessment for reliability and validity before they are used in clinical practice or for research purposes.

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efficacy of sugammadex in patients with a creatinine clearance of less than 30 ml.min )1 [4], but impaired renal function significantly reduced the plasma clearance of sugammadex and the sugammadex-rocuronium complex [5]. Recently, it was shown that neuromuscular blockade could be re-established with 1.2 mg.kg )1 rocuronium as early as 5 min after 4 mg.kg )1 sugammadex. Onset time and duration of neuromuscular blockade block varied according to the time interval between sugammadex reversal and re-administration of rocuronium [6]. The effectiveness of a second dose of rocuronium following sugammadex has yet to be investigated in patients with renal failure.

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