INTRODUCTION: Alzheimer’s disease (AD) is a disorder characterized by cognitive impairment. The brain network in DA can be interrupted by deficiencies in glucose metabolismo. Deep brain stimulation (DBS) is used in Parkinson’s disease (PM), once it modulates motor circuits. Considering this potential, the benefits of this approach in DA must be evaluated1,2. OBJECTIVE: To investigate the potential benefit of stimulating the cerebral fornix (CF) through DBS for patients with AD. METHODS: Controlled and randomized clinical trials (ECCR), in English, performed on humans, in the last 5 years, indexed on PubMed, were selected from the keywords “Deep brain Stimulation” and “Alzheimer Dementia”. This review was registered on PROSPERO by protocol 254506 and the PRISMA recommendation was used to improve its organization. RESULTS: Deeb W et al. (2019) conducted an ECCR on 42 patients with AD receiving DBS in CF, anterior commissure, corpus and sub-corpus callosum, demonstrating that in 48% of them, old experiences were reported. Furthermore, the memories became better as the stimulation increased. Lozano AM et al. (2016), in turn, developed an ECCR on 6 patients receiving DBS in CF, showing increases in glucose metabolism in some cerebral areas after 12 months, contrasting to the expected reduction in AD, especially in > 65 years. It’s noteworthy that the multicenter and double-blind ECCR by Ponce FA (2016) showed the safety of DBS in CF as therapy for AD, similar to that verified in the MP. CONCLUSION: The analyzed evidences suggest a potential cognitive benefit of DBS in the therapeutic management of AD.
Objetivo: Verificar a capacidade do reconhecimento dos sinais e sintomas do Acidente Vascular Cerebral (AVC) por usuários do Sistema Único de Saúde (SUS) de Juiz de Fora. Métodos: Conduziu-se um estudo transversal, observacional com amostra caracterizada por usuários do SUS que frequentavam um hospital de ensino. Selecionou-se 215 voluntários, de ambos os sexos e apresentou-se a eles um vídeo de simulação de AVC, com utilização do questionário qAVC para obtenção dos dados. Resultados: A amostra foi de 65,12% de voluntários do sexo feminino, predominantemente com ensino médio (37,21%), majoritariamente, sem planos de saúde (71,63%). Questionados sobre o ocorrido na simulação, 55,35% indicaram que se tratava de um AVC, não sendo observada diferença entre o sexo e os acertos (OR:1,0; IC95%: 0,56-1,8; p>0,05). Observou-se significância estatística entre aqueles que possuíam planos de saúde e seus acertos (OR:2,1; IC95%:1,1-4,0;p=0,03), além da escolaridade e a capacidade de reconhecimento da condição (p=0,006). 42,79% dos entrevistados afirmaram que acionaria o Serviço de Atendimento Móvel de Urgência, entretanto, 8,37% identificaram “192” como telefone correto. Conclusão: Parcela significativa da amostra desconhece os sinais e sintomas tipicamente associados ao AVC, carecendo de informações sobre seu manejo, além de desconhecer os mecanismos de acionamento dos serviços médicos de urgência.
Introduction: Autistic Spectrum Disorder (ASD) is a neurodevelopmental disorder that affects social communication1 .Music is great for individuals with ASD, because it interacts with the brain, contributing with cognitive and psychosocial benefits2,3. Furthermore, music is emotional and promotes movement synchronization, being a non-pharmacological option for the treatment of ASD3 . Objective: To investigate the positive impacts of using music therapy for cognition in patients with ASD. Methodology: Controlled and randomized clinical trials, in English, performed on humans, in the last 5 years, indexed on PubMed, were selected from the descriptors “autism spectrum disorder” and “music therapy”. This review was registered on PROSPERO by protocol 254495 and the PRISMA recommendation was used to improve its organization. Results: Music therapy was efficient in improving the symptoms of children with ASD, because of the better sensitivity of individuals to music than words4 . In addition, music is able to restore brain connectivity, which is altered in TEA5 . Musical and emotional attunement allows synchronization, integrating the senses and affective regulation, improving self-awareness6. During therapy, there was a reduction in the diagnostic scale of ASD, indicating an improvement in communicative and social skills. Furthermore, it was noted that children became more socially responsive, but there were differences, suggesting the need to balance individual and methodological treatment7 . Finally, music therapy contributes to children’s well-being and health8,9. Conclusion: Evidence suggests that patients with ASD can benefit from music therapy, as it explores and expands the physical and mental limits of the autistic person, stimulating agility, communication and motor control.
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