Follicular mucinosis, also known as alopecia mucinosa, is a cutaneous mucinosis
histologically characterized by accumulation of dermal type mucin in the
pilosebaceous follicle and sebaceous glands. It presents in two forms, a primary or
idiopathic form and a secondary form associated with various benign or malignant
processes. Among the malignant processes, the main association is with mycosis
fungoides. The frequent overlap of clinical, histopathological, immunohistochemical
and molecular biology characteristics makes the correct classification of these
conditions difficult, therefore a long follow-up of all cases is recommended. We
report the case of an adolescent with disseminated lesions and discuss the difficulty
of early identification of secondary follicular mucinosis associated with cutaneous
lymphoma.
Intravascular papillary endothelial hyperplasia is a benign vascular lesion
caused by proliferation of endothelium. It is reactive to thrombotic or
inflammatory stimuli in the vessel wall.We report the case of a 14-yearold male
patient with a violet-colored erythematous tumoral lesion of progressive growth
in the occipital region. The diagnosis of intravascular papillary endothelial
hyperplasia (IPEH) was confirmed by clinical and histopathological findings.
Total lesion exeresis was performed with no recurrence up to date. IPEH presents
clinical importance due to its clinical and histological resemblance to
angiosarcoma. In order to differentiate it from angiosarcoma, distinguishing
features of the benign disease should be considered, such as lack of cellular
atypia and rare mitotic activity.Prognosis is good.
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