A substantial proportion of keratoconjunctivitis is not associated with a detectable adenovirus. The clinical course of those with adenovirus D keratoconjunctivitis is significantly more severe than those with non-adenovirus D species infections or adenovirus-negative keratoconjunctivitis; high viral load at presentation and non-United States origin of participants is associated with poorer clinical outcome.

Olanzapine is second generation antipsychotic drug. It alters affinities for serotonin and dopamine receptors and provides mild sedating and calming effect. It is indicated for the treatment of schizophrenia, acute mania and the prevention of relapse in bipolar disorder. We present a case report of a 65- year- old man with bipolar disorder I, who developed black hairy tongue following treatment with olanzapine and completely recovered after withdrawal of treatment. Awareness about this particular adverse drug reaction will ensure proper management and avoid unnecessary investigations.

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The color of the skin plays very important role in the society especially in India. Switra is a hypopigmentary disorder of skin. Based on the symptoms, Switra can be correlated to Vitiligo of modern science. This Vitiligo affects the estimated 1% of world's population. In the present study 22 cases of Switra were sampled in to 2 groups with 11 patients in each group. The first group of patients received Sramsana therapy followed by internal medicine and lepa. Patients of second group received only lepa. In first group moderate improvement was seen in 72.73 % patients and mild improvement seen in 22.27 % patients. In test group marked improvement was seen in 18.18 % patients whereas marked improvement was observed in 63.64 % patients and mild improvement in 18.18 % patients. When the results of the two groups were compared with unpaired't' test statistically non-significant was obtained which proves the application of lepa alone can produce repigmentation in the mandalas by decreasing their number and size.