A b s t r a c tRecently, several studies have focused on comorbity psychiatric disorders with alcohol and other substance dependence. The Brazilian Association of Studies on Alcohol and Other Drugs proposed the Brazilian Guidelines project. This study review diagnostic and therapeutic criteria to the most prevalent psychiatric comorbidities. Randomized clinical trials, epidemiological, animal studies and other forms of research are reviewed. The main psychiatric comorbidities are studied based on guidelines adopted by other countries and the literature data resumed. Epidemiological aspects, diagnoses, integrated treatment and service organization, as well as specific psychotherapic and pharmacological treatment are discussed. The Brazilian Association of Studies on Alcohol and Other Drugs Guidelines reassures the importance of adequate diagnoses and treatment regarding alcoholic and drug dependent patients suffering of comorbid psychiatric disorders.

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ResumoContexto: Considerando-se que o álcool possui um valor energético, ele tem a habilidade de suprimir as necessidades calóricas diárias de um indivíduo, e/ou levá-lo ao sobrepeso, dependendo da quantidade, freqüência e modo de consumo. Objetivos: Revisar o efeito do álcool no metabolismo energético e suas conseqüências no peso corporal. Métodos: Revisão bibliográfica realizada no sistema MEDLINE (Index Medicus) cruzando os descritores "alcohol" e "weight gain". Resultados: O álcool tem prioridade no metabolismo alterando outras vias metabólicas, incluindo a oxidação lipídica, o que favorece o estoque de gorduras no organismo. Dependendo da forma que ele é metabolizado, sua participação como fonte calórica é diferente. Conclusões: O valor energético dos alimentos adicionados ao consumo alcoólico e o patamar de consumo devem ser observados na relação de ganho de peso. Respostas ao consumo de álcool são diferentes de um indivíduo para o outro e são determinadas por fatores individuais e por possíveis fatores genéticos desconhecidos.Kachani, A.T. et al. / Rev. Psiq. Clín 35, supl 1; 21-24, 2008 Palavras-chaves: Álcool, metabolismo, energia, calorias. AbstractBackground: Due to alcohol's energy content, its intake can meet an individual's daily energy requirements, and/or lead to an individual becoming overweight based on amount, frequency, and pattern of consumption. Objectives: To review alcohol's effect on energy metabolism and its consequences for body weight. Methods: A review of literature was conducted in MEDLINE (Index Medicus), searching with the keywords "alcohol" and "weight gain". Results: Alcohol takes priority in metabolism and affects other metabolic pathways, including lipid oxidation, which facilitates fat accumulation in the body. Depending on the metabolic pathway activated, alcohol can play a different role as an energy source. Conclusions: The energy content of foods consumed together with alcohol and the level of consumption should be monitored to prevent weight gain. Individuals have varying responses to alcohol consumption which are determined by their specific characteristics and possibly by other unknown genetic factors as well.