Background Urinary tract infections (UTI) may affect any part
Latar belakang. Sepsis merupakan masalah kesehatan penting pada anak. Salah satu alat ukur terbaik untuk memperkirakan keparahan penyakit pada anak sepsis adalah skor pediatric logistic organ dysfunction (PELOD). Kadar laktat serum inisial adalah prediktor lain dalam menentukan keparahan penyakit pada anak sepsis yang mudah dilakukan dan hasilnya cepat diperoleh. Tujuan. Mempelajari hubungan antara kadar laktat serum inisial dan skor PELOD pada anak sepsis. Metode. Penelitian analitik dari bulan November sampai Desember 2013 di Instalasi Gawat Darurat Anak (IGDA) RS Prof Dr.R.D Kandou, Manado. Sampel darah diambil untuk pemeriksaan laktat dan dihitung skor PELOD untuk tiap pasien. Untuk analisis selanjutnya digunakan korelasi Pearson dan regresi linear, signifikan apabila p<0,05. Hasil. Terdapat 45 anak sepsis dengan rerata usia 5 tahun. Rerata kadar laktat serum inisial lebih rendah secara bermakna pada pasien yang bertahan hidup dibandingkan pasien yang meninggal (3,67±0,92 berbanding 6,77± 4,62 mmol/L, p=0,013). Rerata skor PELOD juga lebih rendah secara bermakna pada pasien yang bertahan hidup dibandingkan pasien yang meninggal (13,51±13,16 berbanding 25,75±15,82, p<0,01). Didapatkan korelasi rendah antara kadar laktat serum inisial dan skor PELOD (r=0,42, p=0,004). Background. Sepsis remains an important health problem in children. One of the best available tools to estimate the severity of illness in critically ill septic children is The Pediatric Logistic Organ Dysfunction (PELOD) score. Early lactate serum is a potentially feasible and clinical useful predictor of mortality in sepsis patients. Objective. To study the correlation between initial lactate serum and PELOD score in children with sepsis. Methods. We performed a prospective analytic study from November to December 2013 in Pediatric Intensive Care Unit (PICU) Prof. dr. R. D. Kandou Hospital, Manado. Blood sample was taken for lactate examination and PELOD score for each patient was calculated. Further analysis was done using Pearson correlation and linear regression. Test results were statistically significant if p < 0.05. Results. There were 45 children with sepsis, with mean age of 5 years old. Mean initial lactate serum were significantly lower in survivors compared with non-survivors (3.67±0.92 vs 6.77 ± 4.62 mmol/L, p=0.013) and mean PELOD score were also significantly lower in survivors compared with non-survivors (13.51 ± 13.16 vs 25.75±15.82, p <0.01). We found a significant positive correlation between initial lactate serum and PELOD score (r= 0.42, p=0.004). Conclusion. There was a positive correlation between initial lactate serum and PELOD score in children with sepsis. Sari Pediatri 2016;18(3):192-7
Latar belakang. Seiring meningkatnya angka harapan hidup anak dengan leukemia limfoblastik akut (LLA), kardiotoksisitas akibat kemoterapi seperti antrasiklin menjadi semakin penting. Evaluasi berkala fungsi sistolik ventrikel kiri melalui fraksi ejeksi (FE) dan fraksi pemendekan (FP) direkomendasikan untuk pemantauan efek samping kardiotoksisitas antrasiklin.Tujuan. Penelitian ini bertujuan untuk melihat hubungan antara dosis kumulatif doksorubisin dengan fungsi sistolik ventrikel kiri pada penyintas LLA anak. Metode. Penelitian ini menggunakan metode kohort retrospektif dengan menilai perubahan FE dan FP menggunakan ekokardiografi pada penyintas LLA pada bulan Juli-September 2016 di bagian Ilmu Kesehatan Anak, RSU Prof. dr. R. D. Kandou, Manado. Pengambilan sampel dilakukan dengan cara total sampling. Analisis statistik dilakukan dengan menggunakan korelasi Pearson.Hasil. Terdapat total 18 penyintas LLA yang diteliti, termasuk 12 risiko standar dan 6 risiko tinggi. Fungsi sistolik ventrikel kiri semua penyintas masih dalam batas normal (FE 74,20 ± 11,37 %, FP 42,61 ± 9,98 %). Ditemukan adanya hubungan negatif sedang yang bermakna antara dosis kumulatif doksorubisin dan fungsi sistolik ventrikel kiri [FE (r=-0,532, p=0,012) dan FP (r=-0,518, p=0,014)]. Kesimpulan. Terdapat hubungan negatif antara dosis kumulatif doksorubisin dan fungsi sistolik ventrikel kiri pada penyintas LLA anak. Panduan lokal diperlukan untuk evaluasi ekokardiografi secara berkala pada penyintas LLA anak di Indonesia.
A 7-months-old girl presented with bloody diarrhea and vomiting. She had been fed with red rice since she was 5 months old. She was restless, defecated red currant jelly stool and sausage-shaped mass was palpable on the inferior of umbilical region. The ultrasound showed a 3.16 × 2.58 cm mass with a target-like appearance which is consistent with intussusception. She underwent exploratory laparotomy, invagination release (milking) and appendectomy. Pathologic examination of the lymph node on the mesenteric side of caecum revealed lymphoid tissue hyperplasia. The introduction to solid food before 6 months in this patient was suspected as the predisposing factor of the intussusception. More effective counseling about the timing of solid food introduction by pediatrician or primary health care provider may prevent other similar cases like this from happening.
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