The 3 groups were similar in age, body mass index, serum prostate specific antigen and total prostate volume. There was no significant difference in pain scores during probe insertion, local anesthetic injection, and transrectal ultrasonography between three groups. Pain during prostate biopsy was significantly lower in group 1 and 2 than group 3. There was no significant difference during prostate biopsy between group 1 and 2. The mean pain score during biopsy was no significant difference between the mean pain scores, 30 minutes after biopsy among three groups. There were no major complications. CONCLUSIONS: PPB under Doppler ultrasound guidance does not improve patient pain during biopsy compared with PNB.
Preliminary study indicates MR findings which can help differentiate a BPH nodule from transitional zone prostate cancers which could help direct biopsy in the large and growing number of people suspected of having prostate cancer. Further work will be needed for validation.
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