FCM was effective in increasing the key blood indices with no adverse outcomes in children less than 14 years of age, with a range of different conditions, majority with gastrointestinal disorders such as IBD. What is Known: • Ferric carboxymaltose (FCM) given via the intravenous (IV) route has been used widely in adults for the treatment of iron deficiency anaemia. • Sparse data exists on FCM use in paediatric population, including young children What is New: • FCM infusion should be considered as a means of iron administration in the paediatric population less than 14 years of age • No adverse outcomes were recorded following FCM in a young paediatric population (less than 14 years of age); the majority of whom had gastrointestinal disorders.
Cso reacts with [15]crown-5-substituted diphenylcarbene precursors to give the corresponding benzo-crowned methanofullerenes 7, which were isolated preparatively and characterized. Two isomers ?a and 7b, which equilibrate to ?a upon heating, were detected by HPCL and separated. The dimer-type arrangements.[
Wittig Synthesis and X‐Ray Structure of a 26‐Membered Macrocycle Containing two Bipyridine Units
Wittig‐type macrocyclization of bipyridinedicarbaldehyde 5 with bis(phosphonium bromide) 6 leads to the new bipyridinophanes 7 8. The X‐ray structural analysis of 8 reveals a step‐type conformation, which according to 1H‐NMR results is also present in solution.
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