Summary
In vertebrate vision, the tetrachromatic larval zebrafish permits non-invasive monitoring and manipulating of neural activity across the nervous system
in vivo
during ongoing behavior. However, despite a perhaps unparalleled understanding of links between zebrafish brain circuits and visual behaviors, comparatively little is known about what their eyes send to the brain via retinal ganglion cells (RGCs). Major gaps in knowledge include any information on spectral coding and information on potentially critical variations in RGC properties across the retinal surface corresponding with asymmetries in the statistics of natural visual space and behavioral demands. Here, we use
in vivo
two-photon imaging during hyperspectral visual stimulation as well as photolabeling of RGCs to provide a functional and anatomical census of RGCs in larval zebrafish. We find that RGCs’ functional and structural properties differ across the eye and include a notable population of UV-responsive On-sustained RGCs that are only found in the acute zone, likely to support visual prey capture of UV-bright zooplankton. Next, approximately half of RGCs display diverse forms of color opponency, including many that are driven by a pervasive and slow blue-Off system—far in excess of what would be required to satisfy traditional models of color vision. In addition, most information on spectral contrast was intermixed with temporal information. Taken together, our results suggest that zebrafish RGCs send a diverse and highly regionalized time-color code to the brain.
Outlines the key areas which manufacturing organisations should consider in order to improve the effectiveness of training programmes for production operators. The authors carried out a study of UK‐based manufacturing companies to identify current evaluation methods, and identify the predominant barriers to the implementation of effective training programmes. The research concluded that most of the companies believed that their training programmes did not realise the full potential in terms of higher productivity, better on‐the‐job performance, and improved quality. Causal factors were found to be inadequate training objectives and evaluation mechanisms, which stem from a number of barriers. Proposes a training programme measurement model, which has been adapted from existing concepts, and could be applied by manufacturing organisations as a framework for carrying out appropriate evaluation activities. Concludes with some recommendations for future policy, and areas of further research in the implementation of training programmes in manufacturing organisations.
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