The in situ prepared complex based on copper(II) sulfate and 1,10-phenanthroline (phen) and its performance in the catalytic oxidation of veratryl alcohol (3,4-dimethoxybenzyl alcohol) to veratraldehyde with O 2 in alkaline aqueous solutions have been studied. In aqueous solution, the structure of Cu-phen complexes varies with reaction conditions; by changing either the copper-to-ligand molar ratio or the pH, the amount of coordinated 1,10-phenanthroline and hydroxido ligands in the coordination sphere of copper can be altered in a controlled manner. The highest activities are achieved in the pH range 12.6-13.3, which correlates with the presence of the [Cu(phen)(OH) 2 ] species according to
(R)‐Cycloserine (I) is converted into the protected aminoisoxazolidine (VIII) which reacts with the trifluorooxoquinolinecarboxylic acid (XI), prepared from pentafluorobenzyl alcohol (IX), to produce a mixture of the isoxazolidinyl derivative (XII) and the amine (XIII).
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