This retrospective study was designed to evaluate the outcome of pregnancies in women diagnosed with systemic lupus erythematosus (SLE) followed in a tertiary fetal-maternal center. Data were collected from clinical charts between January 1993 and December 2007, with a total of 136 pregnancies (107 patients). Mean maternal age was 29 years, with the vast majority of patients being Caucasian. Most patients were in remission 6 months prior to pregnancy (93%) and the most frequently affected organs were the skin and joints. Renal lupus accounted for 14% of all cases. Twenty-nine percent of patients were positive for at least one antiphospholid antibody (aPL) and nearly 50% had positive SSa/SSb antibodies. All patients with positive aPL received low-dosage aspirin and lowmolecular-weight heparin (LMWH). There were no pregnancy complications in more than 50% of cases and hypertensive disease and intrauterine growth restriction were the most common adverse events. There were 125 live births, one neonatal death, eight miscarriages, and three medical terminations of pregnancy. Preterm delivery occurred in 25% of pregnancies. Our results are probably the conjoined result of a multidisciplinary approach together with a systematic management of SLE pregnancies, with most patients keeping their prior SLE medication combined with low-dosage aspirin and LMWH in the presence of aPL.

Todos os autores declaram não ter qualquer tipo de conflito de interesses relativamente ao presente manuscrito.

Introduction/Background Accurate preoperative diagnosis of adnexal mass helps to estimate the risk of malignancy and enables one to choose the best management approach. Prediction models have been developed to assist clinicians to triage patients to appropriate treatment pathways; and both ADNEX and GI-RADS have shown good accuracy; no study has been done comparing the two systems. The main objective was to evaluate and compare the diagnostic accuracy of Assessment of Different Neoplasias in the Adnexa (ADNEX) Model and Gynecology Imaging Reporting and Data System (GI-RADS) in preoperative assessment of adnexal masses taking histopathology as gold standard.Methodology In this analytical study, sixty patients more than 14 years of age undergoing surgery for adnexal masses were assessed with transabdominal and transvaginal ultrasound 2-3 days prior to surgery. In cases were surgery was not possible, biopsy was performed to confirm histology. Pregnant women, women with previously established ovarian pathology were excluded. Score probability of the Assessment of Different Neoplasias in the Adnexa (ADNEX) model and Gynaecology Imaging Reporting and Data System (GI-RADS) category was calculated based on the ultrasound parameters of adnexal mass. Results For ADNEX model sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy was 87.50%, 91.7%, 87.50%, 91.7% and 90.0% respectively. The diagnostic performance of GI-RADS category in terms of sensitivity, specificity, PPV, NPV and accuracy was 95.8%, 61.1%, 62.2%, 95.7% and 75.0% respectively. Overall the diagnostic performance of ADNEX model was better compared to GI-RADS in terms of specificity and positive predictive value with significant difference (p<0.05). The Area under curve (AUC) was 0.957 and 0.919 for ADNEX and GIRADS respectively (p=0.252).

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Electronic poster abstractsshowed an extensive temporo-parietal tumour of 8 cm with diffuse cerebral edema. The patient underwent an extensive tumour resection but it was incomplete. She received an antiepileptic treatment. The histopathological examination showed a grade-4 glioblastoma. Because of the need for radioadjuvant therapy, the termination of the pregnancy was discussed with the patient who refused this medical advice. During the subsequent fellow-up visits, she did not present any particular complaint and the delivery was scheduled by Caesarean section at the 34th week of gestation. Postpartum, the patient was referred to another centre for adjuvant chemotherapy.EP42.17 Vacuum-assisted stereotactic breast biopsy and its role in the management of suspicious microcalcifications