Cancer Genetics Program for their help in this endeavor. We especially thank Kevin Sweet, M.A. for his help with data collection. associated with the stress associated with the counseling and/or testing situation, and psychological distress for both probands and study partners.

Health sciences curricula are, by definition, built on a foundation of scientific knowledge and inquiry. Professional programs in fields such as medicine, pharmacy, nursing, physical/occupational therapy, and dentistry purport to provide students with the ability to translate scientific knowledge and understanding into clinical practice, for improving the health and well-being of patients. Indeed, the scientific underpinning of each health profession is a point of pride, a reason these roles exist in the first place and are accorded the prestige of being called a "profession".

Objectives: To describe and examine the experiences of pharmacists who had become physicians. Method: A key informant approach was utilized to identify potential participants in this study, which involved a semistructured interview. Field notes and transcripts were produced, coded and categorized, and an inductive analysis method was used to generate themes that were confirmed with subsequent interviews.Results: A total of 32 pharmacist-physicians participated in this study. All participants had practiced as pharmacists prior to beginning medical school. For most participants, intrinsic motivational factors to study medicine were very strong, while extrinsic motivational factors were cited as reasons to study pharmacy. The experience of medical school, and approaches to medical education were compared and contrasted with pharmacy; while pharmacy was described as more collegial, friendly and supportive, medical (particularly practice-based) education was described as more relevant and focused. Striking differences emerged between male and female participants regarding satisfaction with the decision to pursue medicine as a career; male participants were generally positive about their decision, while female participants were somewhat more nuanced or ambivalent regarding change in their profession.Conclusions: Examining the experiences of individuals who are both physicians and pharmacists provides an informative vehicle for examining differences and similarities in professional education, training and culture. While further work is necessary to more clearly examine these issues, this study provides an important insight into the ways in which pharmacists and physicians relate to one another and their own professional cultures.

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The Southeast Partnership for Improving Research and Training in Cancer Health Disparities (SPIRIT-CHD) unites Louisiana State University Health Sciences Center (LSUHSC) and Moffitt Cancer Center (MCC) to advance translational research on cancer health disparities and to establish a Cancer Research Education Program (CREP). The CREP addresses a national priority to develop an educational training pipeline for one-on-one mentoring of undergraduates and medical students by a diverse group of LSUHSC and MCC faculty with unique expertise to conduct cancer health disparities research and outreach in underserved communities. The CREP supports 8-week internships providing: (1) hands-on summer research experiences; (2) a curriculum focusing on biobanking, precision medicine, and cancer health disparities; and (3) community outreach experiences in underserved communities. The curriculum includes web-based training modules, immersion experiences (e.g., biobank tour), professional development workshops, and learning activities (e.g., book and journal clubs). Data from the students' pre/post summative (impact/outcome) evaluations determine the acceptability and impact of these research and educational activities, students' knowledge, career aspirations, goal attainment, and their satisfaction based on nationally normed scales. Baseline and post-training data will be analyzed in August, at training completion, to assess program impact. Long-term yearly follow-up data will focus on the impact of CREP on student career trajectories. These data will help modify the CREP for years 2-4 of the SPIRIT-CHD. Seventy-five percent of the student participants in the first cohort were female. Students self-identified as Black/African American non-Hispanic (62.5%), White Hispanic (25%), and Asian non-Hispanic (12.5%). Student projects included genomic, immunologic, and cellular wet-lab research (analyzing proliferation of renal cell carcinoma, RNA sequencing and bioinformatics of Luminal B breast carcinomas, expression differences of polyamine enzymes in prostate cancer) and clinical studies (detection, prevention, and treatment of anal cancer in HIV-positive populations). Dry-lab projects focused on the analysis of Behavioral Risk Factor Surveillance System to assess policy-related trends in colorectal cancer screenings, studying the effectiveness of barbers as lay health educators for skin cancer prevention, and smoking cessation among Hispanics. CREP students also participated in cancer education outreach events to explain their projects to the communities at an elevated risk for certain types of cancer. This program has applicability to undergraduate and medical students nationwide on best practices for efficacious training in cancer health disparities, precision medicine, and biobanking. Ultimately, these efforts will enhance the diversity of the cancer research workforce, while contributing to the reduction of cancer health disparities. Citation Format: Fern Tsien, Paula Gregory, Gwendolyn Quinn, Vani N. Simmons, Z'Kera Sims, Megan E. Sutter, Ayesha Umrigar, Arnold H. Zea, Cathy Meade, Clement K. Gwede. The Cancer Research Education Program (CREP): Training the next generation of cancer health disparities researchers through the Southeast Partnership for Improving Research and Training in Cancer Health Disparities (SPIRIT-CHD) [abstract]. In: Proceedings of the Eleventh AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2018 Nov 2-5; New Orleans, LA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl):Abstract nr A065.