RESUMO -Apresentamos o estudo clínico-epidemiológico de dois pacientes e metanálise (período 1977-2000) sobre a comorbidade entre síndrome de Down (SD) e síndrome de "moyamoya" (SMM). Entre os 42 pacientes catalogados no presente estudo, a metanálise permitiu verificar: maior número de publicações de pesquisadores do Japão e Estados Unidos, seguidos pelo Brasil e Itália; predomínio do acidente vascular cerebral (AVC) em lactentes e pré-escolares; sintomatologia inaugural, hemiparesia (78,6%), distúrbio da fala (26,2%); predomínio de infarto isquêmico (76,2%); episódios isquêmicos recorrentes (62%); comprometimento bilateral (83,3%). Esta análise permitiu concluir que, na investigação clínico-neurológica de pacientes com SD e episódios de hemiparesia aguda, a SMM deve ser incluída como diagnóstico mais provável . PALAVRAS-CHAVE: doença cerebrovascular, síndrome de Down, moyamoya. Moyamoya and Down syndrome: study conducted by meta-analysisABSTRACT -We present a clinic-epidemiological study of two patients and meta-analysis (period 1977-2000 ) of the co-morbidity of the Down syndrome (DS) and moyamoya syndrome (MMS). Among the 42 patients listed in this survey, meta-analysis permitted to find the highest number of publications by researchers from Japan and United States, followed by Brazil and Italy; prevalence of cerebrovascular disease in suckling and pre school children; first symptomatology was hemiparesis (78.6%), speech disorders (26.2%); ischemic infarction (76.2%); recurring ischemic episodes (62%); bilateral impairment (83.3%). This analysis led to the conclusion that in the clinic-neurological investigation of DS patients with acute hemiparesis episodes, MMS should be included as the most probable diagnosis.KEY WORDS: cerebrovascular diseases, Down syndrome, moyamoya syndrome. Dr. Paulo Alves Junqueira -Rua Mário Borin 500 -13209-030 Jundiaí SP -Brasil. E-mail: ppaj@terra.com.brPacientes com diagnóstico de síndrome de Down (SD) e anormalidades cerebrovasculares semelhantes às detectadas na doença "moyamoya" têm sido sistematicamente relatadas na literatura nos últimos 20 anos. Fukushima e col.¹ encontraram um caso de síndrome de "moyamoya" (SMM) dentre 532 pacientes com SD e Nishimura e col.² um entre 400. Segundo Kawai³ estes dados são três vezes superiores à incidência da doença "moyamoya" na população geral. Em 1977, Schrager e col. 4 publicaram o primeiro caso desta associação, relatando o estudo de menina de três anos que desenvolveu hemiplegia aguda acompanhada de cegueira cortical. É importante realçar que, no Brasil, Schultz e col.5 , em 1981, documentaram o segundo caso da literatura, tecendo considerações sobre a etiopatogenia desta associação.Atualmente, no consenso para o diagnóstico da doença "moyamoya", indicados pelo Comitê de Pesquisa do Japão (1988) é necessário o preenchimento dos seguintes critérios: 1-Estenose ou oclusão da artéria carótida interna ou das artérias cerebrais anterior e média; 2-Rede vascular anormal, identificada durante a fase arterial da angiografia; 3-Comprometi...

RUBENS REIMÃO** The purpose of this research was to verify sleep disorder events in the population of Furnas do Dionísio, State of Mato Grosso do Sul (MS), Brazil. This population of that rural and isolated black community, in the Municipality of Jaraguari, MS, has been assessed. Interviews made in the period of January 1999 to January 2000 have been used. Census-type sampling has been used, assessing all community inhabitants, with age of 18 or more years (Furnas Group), in a total of 120 subjects. The Control Group has been collected in a neighboring rural zone, in the same Municipality, also using Census-type sampling and the same age range, in a total 101 subjects. Populations have been compared in relation to age and gender. Furnas Group was composed by 97.5% of non-white people and the Control Group by 3.9% of non-white people (p = 0.001). The instruments used were the following: (a) Giglio adult sleep questionnaire (Giglio questionnaire); (b) Hamilton Depression Rating Scale; (c) CAGE scale, to assess the alcoholism behavior. In conclusion, the usual pattern of night sleep in Furnas Group showed a trend to have sleeping and wakening times earlier than those described in urban populations. Furnas Group sleeping times in the weekends, and wakening times, both in the weekdays and in the weekends, later than those of the Control Group. The usual standard diurnal sleep, in Furnas Group, showed a prevalence of regular siesta, similar to that observed in the Control Group. Both groups have siesta culture, since 66.3% of the Furnas Group and 59.4% of the Control Group regularly sleep during daytime. The events presented at the research time verified when comparing Furnas Group with the Control Group, evidence the following sleep disorders, with higher access of Furnas Group: wish to change the sleeping habits; dissatisfaction with the sleeping place; complaints of sleeping problems; difficulty in falling asleep; irresistible diurnal sleep; sleepwalking; swallowing difficulty and suffocation during sleep; asthma crisis during sleep; sleep paralysis; nightmare; current insomnia. None of the sleep disorders have been found more in the Control Group

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