Aortopulmonary window (APW) is rare a congenital heart disease accounting for 0.1%-0.2% of all congenital heart defects. The 35% of the APW has been associated with wide variety of other structural heart diseases such as ventricular septal defect, persistent ductus arteriosus, arch anomalies and coronary artery anomalies. To the best of our knowledge, only six cases of APW with pulmonary atresia with ventricular septal defect has been described in the literature. It resembles the type 1 truncus arteriosus, and differentiation from this condition is important prior to surgical correction. We present a case of 14-year-old girl child; she was diagnosed with APW with pulmonary atresia with ventricular septal defect and D transposition of great arteries with the help of echocardiography, cardiac catheterisation and cardiac CT.
Statins are commonly used drugs for primary and secondary prevention of coronary artery disease. Statins associated muscle adverse events are not uncommon. Myalgias and myopathy occur with a frequency of 2 to 11 percent.1 However, severe myonecrosis and clinical rhabdomyolysis are much rarer (0.5 percent and less than 0.1 percent, respectively) [1,2]. Statin intolerance was neglected during routine clinical practice. We report a case of 58 year old male who developed severe proximal muscle weakness after giving high dose of atorvastatin.
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