Tuberculosis (TB) of the breast is a very rare pathology. The clinical presentations of this disease are manifold, often mimicking carcinoma of the breast. We conducted a retrospective analysis of 20 women with TB of the breast receiving care at the mastology clinic at Getúlio Vargas Hospital, PI, Brazil, between 1994 and 2007. The clinical presentation of the disease, the diagnosis and the response to specific treatment were analyzed. Most of the patients were of reproductive age, with the disease affecting the right breast in eleven patients (55%) and the left breast in nine patients (45%). Palpable nodules were present in five patients (25%) and fistulae in 15 (75%). The mean time between onset of symptoms and diagnosis was 7.7 months (range 3-12 months). Skin testing with purified protein derivative of tuberculin was strongly reactive in all patients, six (30%) of whom were breastfeeding. Diagnosis was confirmed by histopathology and all patients were satisfactorily treated with a combination of rifampicin, isoniazid and pyrazinamide. In the present study, TB of the breast presented predominantly as breast abscesses and fistulae and responded satisfactorily to treatment with anti-TB drugs.
Embryonal rhabdomyosarcomas of the uterus are extremely rare malignant tumors and their association with uterine inversion is even rarer. The present case report refers to a 15-year-old Brazilian girl admitted to hospital with a 3-month history of transvaginal bleeding and a mass protruding from the vaginal introitus. Following biopsy of the lesion and confirmation of the diagnosis of embryonal rhabdomyosarcoma, the patient was submitted to total abdominal hysterectomy followed by chemotherapy and radiotherapy. The patient died 9 months after surgery. Embryonal rhabdomyosarcoma of the uterus is very rare and extremely aggressive. According to a published work review, there has been only one report to date on the association of embryonal rhabdomyosarcoma of the uterus and uterine inversion.
Embryonal rhabdomyosarcomas of the uterus are extremely rare malignant tumors and their association with uterine inversion is even rarer. The present case report refers to a 15‐year‐old Brazilian girl admitted to hospital with a 3‐month history of transvaginal bleeding and a mass protruding from the vaginal introitus. Following biopsy of the lesion and confirmation of the diagnosis of embryonal rhabdomyosarcoma, the patient was submitted to total abdominal hysterectomy followed by chemotherapy and radiotherapy. The patient died 9 months after surgery. Embryonal rhabdomyosarcoma of the uterus is very rare and extremely aggressive. According to a published work review, there has been only one report to date on the association of embryonal rhabdomyosarcoma of the uterus and uterine inversion.
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