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Mood changes over the bulimic binge–purge cycle were studied in retrospective questionnaire reports of patients, 16 with and 34 without concurrent affective disorder. Moods clearly differed over phases. Mood reports depicted the period between the binge and purge as most unpleasant, with low energy/excitement and security/relief and high panic/helplessness and guilt/disgust/anger. Feelings after the purge were relatively calm and pleasurable, with low panic/helplessness and excitement/energy and high security/relief. Patients with affective disorder did not differ from those without affective disorder in their mood changes during the cycle.

As part of an ongoing prospective study to correlate mother and infant outcome with social isolation during pregnancy, the Schedule for Affective Disorders, SADS-C, was administered to twenty-seven psychotic patients late in pregnancy. Extensive standardized evaluation of life stresses and social supports included a Prenatal Interview with sixty items relating to demographics, drug use, health and obstetrical history, family involvement and development expectations of the infant, and a thirty-item Difficult Life Circumstances questionnaire. In this sample the patients' previous life adjustments were stabilized by their pregnancy unless the pregnancy itself created personal stress for the patient. Higher scores on Difficult Life Circumstances were found to be associated with more psychiatric symptomatology. Symptoms of pregnancy confounded SADS-C items measuring vegetative signs of depression. One group of items on the SADS-C appeared to selectively identify a subset of women whose underlying affective symptomatology was potentiated by pregnancy. A second group of items identified women whose symptoms appeared to be reactive to current situational strains.

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