A NO sensing tip is made by inserting two parallel optical fibers inside a poly 2-hydroxyethyl methacrylate (PolyHEMA) hydrogel waveguide mixed with the probe molecule 1, 2-Diaminoanthraquinone (DAQ). There is a length difference of 1 mm between the two fibers, and the light has to propagate through the difference from the short fiber to the long fiber. The total cross section area of the active hydrogel waveguide embedded with the fibers is only 3mm x 1.2 mm. For practical use the tip is housed in a needle for mechanical protection and the sensing tip is able to detect aqueous NO concentration around 1 μM with time resolution about 5 minutes. Such a sensing tip can be used to monitor the medical conditions inside the brain after a stroke or a brain injury.
We experimentally demonstrate Nyquist wavelength-division-multiplexed (WDM) channels with a low signal-to-noise ratio (SNR) difference based on flat electro-optic combs (EOCs), which reduce the interchannel crosstalk penalty in Nyquist-WDM transmission with no guard band. The five Nyquist-WDM channels are generated through the insertion of uniform and coherent lines around each line of the EOCs from a dual-parallel Mach–Zehnder modulator. For the five channels, the normalized root-mean-square error of optical sinc-shaped pulses at a repetition rate of 9 GHz is between 1.23% and 2.04%. The SNRs of the Nyquist signal can be better than 30 dB by using flat EOCs with a narrow linewidth as WDM sources, and the difference in SNR is less than 0.6 dB for the WDM channels. The transmission performance of five Nyquist-WDM channels with no guard band is compared in a 56 km fiber link. The results show that our scheme provides a minimum interchannel sensitivity penalty of 0.7 dB at the forward-error-correction limit. The Nyquist-WDM channels with low SNR difference can effectively improve the communication performance of the Nyquist-WDM system.
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