The aim of the study was to evaluate the sensitivity of patients' self-sampled vaginal specimens, first-catch urine (FCU), combined vaginal/FCU specimens and endocervical specimens for detecting chlamydial infection in women. Women attending sexually transmitted disease clinics, youth clinics and a women's health clinic were enrolled. They self-collected a vaginal specimen with two swabs, which were placed into a sterile tube and into a tube containing a buffer medium, respectively. An FCU sample was collected and aliquoted into both an empty tube and the tube containing the vaginal swab. A clinician collected an endocervical swab. The samples were sent to laboratories for analysis using polymerase chain reaction testing and strand displacement amplification testing, respectively. The sensitivities calculated in all 171 Chlamydia trachomatis-infected women were equal for endocervical specimens (97.1%), vaginal specimens (96.5%) and combined vaginal/FCU specimens (95.3%), whereas the sensitivity for FCU was significantly lower (87.7%). The sensitivity of vaginal specimens for the detection of C. trachomatis is as high as that of combined vaginal/FCU specimens.

Syringoma exclusively located to the penis is an extraordinary rare dermatological condition, and only 6 patients with syringoma exclusively located to the penis have been published previously. Light microscopical examination of routine hematoxylin and eosin-stained sections from punch biopsies with adequate depth from 2 patients was performed. Classical syringoma was diagnosed. The lesions occurred in an eruptive fashion in both patients on the dorsal and lateral aspects of the penis shaft. There was a variation in clinical appearances ranging from yellow-white papules, a few millimeter in size to, in one of the patients, formation of several slightly elevated plaques, 10 mm in size, with a brownish-red color. We describe clinicopathological features of 2 patients with syringoma exclusively located to the penis. These are compared with all the previously published cases. Clinical and histopathological differential diagnoses are discussed, and a literature review is presented.