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This report presents the following population-based measures: incidence rates, mortality rates, and relative survival rates (for more information on definitions of terms and Estimation of Expected Numbers of Brain and Other CNS Tumors in 2017 and 2018Estimated numbers of expected malignant and non-malignant brain and other CNS tumors were calculated for 2017 and 2018. To project estimates of newly diagnosed brain and other CNS tumors in 2017 and 2018, age-adjusted annual brain tumor incidence rates were generated for 2000-2014 for malignant tumors, and 2006-2014 for nonmalignant tumors. These were generated by state, age, and histologic type. Joinpoint 4.2.0.2 32 was used to fit regression models to these incidence rates, 33 which were used to predict numbers of cases in future years using the parameter from the selected models. Joinpoint regression allows for multiple lines to be fit to incidence data across time, rather than assuming a consistent trend across the whole period. The points where these lines intersect are called 'joinpoints'. The models allowed for a maximum of 2 joinpoints (1 for non-malignant tumors), a minimum of 3 observations from a joinpoint to either end of the data, and a minimum of 3 observations between joinpoints. 34 Modified Bayesian Information Criterion procedures included in Joinpoint were used to select the best fitting model. Overall total rates presented are based on total malignant and