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Since June, 2018, the Gravity Recovery and Climate Experiment Follow-On (GRACE-FO) is extending the 15-year monthly mass change record of the GRACE mission, which ended in June 2017. The GRACE-FO instrument and flight system performance has improved over GRACE. Better attitude solutions and enhanced pointing performance result in reduced fuel consumption and gravity range rate post-fit residuals. One accelerometer requires additional calibrations due to unexpected measurement noise. The GRACE-FO gravity and mass change fields from June 2018 through December 2019 continue the GRACE record at an equivalent precision and spatiotemporal sampling. During this period, GRACE-FO observed large interannual terrestrial water variations associated with excess rainfall (Central US, Middle East), drought (Europe, Australia), and ice melt (Greenland). These observations are consistent with independent mass change estimates, providing high confidence that no intermission biases exist from GRACE to GRACE-FO, despite the 11-month gap. GRACE-FO has also successfully demonstrated satellite-to-satellite laser ranging interferometry. Plain Language Summary Mass change is a fundamental climate system indicator and provides an integrated global view of how Earth's water cycle and energy balance are evolving. The Gravity Recovery and Climate Experiment (GRACE) mission monitored mass changes every month from 2002 through 2017. Since June 2018, GRACE Follow-On (GRACE-FO) continues this data record, tracking and monitoring changes in ice sheets and glaciers, near-surface and underground water storage, as well as changes in sea level and ocean currents. GRACE-FO instruments have been successfully calibrated and are providing new monthly mass change observations at a consistent spatial resolution and data quality with GRACE. Since its launch, GRACE-FO has measured record land water storage changes in 2018 and 2019 in response to extreme heat waves and droughts over Europe and Australia, as well as to extreme rainfall events over the United States and Middle East. In the summer of 2019, GRACE-FO measured record-level Greenland mass loss rates. A novel laser ranging interferometer was successfully demonstrated on GRACE-FO, laying the groundwork for improved future satellite gravity observations.

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Molecular patterning processes taking place in biological systems are challenging to study in vivo because of their dynamic behavior, subcellular size, and high degree of complexity. In vitro patterning of biomolecules using nanolithography allows simplification of the processes and detailed study of the dynamic interactions. Parallel dip-pen nanolithography (DPN) is uniquely capable of integrating functional biomolecules on subcellular length scales due to its constructive nature, high resolution, and high throughput. Phospholipids are particularly well suited as inks for DPN since a variety of different functional lipids can be readily patterned in parallel. Here DPN is used to spatially pattern multicomponent micro- and nanostructured supported lipid membranes and multilayers that are fluid and contain various amounts of biotin and/or nitrilotriacetic acid functional groups. The patterns are characterized by fluorescence microscopy and photoemission electron microscopy. Selective adsorption of functionalized or recombinant proteins based on streptavidin or histidine-tag coupling enables the semisynthetic fabrication of model peripheral membrane bound proteins. The biomimetic membrane patterns formed in this way are then used as substrates for cell culture, as demonstrated by the selective adhesion and activation of T-cells.

Aim To investigate the contribution to range filling, range extent and climatic niche space of species of information contained in the largest databank of digitized biodiversity data: the global biodiversity information facility (GBIF). We compared such information with a compilation of independent distributional data from natural history collections and other sources. Location Europe. Methods We used data for the hawkmoths (Lepidoptera, family Sphingidae) to assess three aspects of range information: (1) observed range filling in 100 km × 100 km grid cell squares, (2) observed European range extent and (3) observed climatic niche. Range extents were calculated as products of latitudinal and longitudinal extents. Areas derived from minimum convex polygons drawn onto a 2‐dimensional niche space representing the two main axes of a principal component analysis (PCA) were used to calculate climatic niche space. Additionally, record‐based permutation tests for niche differences were carried out. Results We found that GBIF provided many more distribution records than independent compilation efforts, but contributed less information on range filling, range extent and climatic niches of species. Main conclusions Although GBIF contributed relevant additional information, it is not yet an effective alternative to manual compilation and databasing of distributional records from collections and literature sources, at least in lesser‐known taxa such as invertebrates. We discuss possible reasons for our findings, which may help shape GBIF strategies for providing more informative data.