BackgroundAlthough immune system plays a key role in the pathogenesis of both endometriosis and ovarian cancer, its function is different. Therefore, we hypothesized, that selected immune parameters can serve as diagnostic markers of these two conditions. The aim of this study was to compare serum and peritoneal fluid concentrations of sHLA-G, IL-10 and TNF-alpha in women with selected ovarian pathologies: benign serous cysts, endometrioma and malignant tumors. Clinical significance of using them for diagnostic purposes in women with serous ovarian cysts, endometriosis, and ovarian cancer, which in the future may improve the early diagnosis of ovarian diseases.Case PresentationThe study included women treated surgically for benign serous ovarian cysts, ovarian endometrioma and serous ovarian adenocarcinomas. Peripheral blood and peritoneal fluid samples were obtained intraoperatively. Patients with benign serous cysts, endometrioma and ovarian malignancies did not differ significantly in terms of their serum and peritoneal fluid concentrations of sHLA-G. Ovarian cancer patients presented with significantly higher median serum concentrations of IL-10 and TNF-alpha than other study subjects. Median concentrations of IL-10 and TNF-alpha in peritoneal fluid turned out to be the highest in ovarian cancer patients, followed by women with endometrioma and subjects with benign serous cysts. All these intergroup differences were statistically significant. Irrespective of the group, median concentrations of sHLA-G, IL-10 and TNF-alpha in peritoneal fluid were higher than serum levels of these markers.ConclusionsElevated serum and peritoneal fluid concentrations of IL-10 and TNF-alpha distinguish ovarian malignancies and endometriomas from benign serous ovarian cysts. In contrast to endometriosis, ovarian malignancies are characterized by elevated peritoneal fluid concentrations of IL-10 and TNF-alpha, elevated serum concentrations of IL-10 and low serum levels of TNF-alpha. Serum and peritoneal fluid concentrations of sHLA-G have no diagnostic value in differentiating between ovarian malignancies and endometriomas.

The load-bearing capacity of natural airfield pavement has a direct impact on the safety of air operations. Unfortunately, the field tests often indicate that the load-bearing capacity of natural airfield pavements is not sufficient. In this case, it is necessary to reinforce them in order to meet the requirements set out in international documents. It is important that the method of reinforcing the subsoil is fast and as noninvasively as possible. There are many methods of reinforcing the subsoil, however, they are expensive and time-demanding, which involves turning off the airport for a long time. Airfield geocells made of recycled plastics discussed in the article seem to be the optimal solution due to the quick implementation of their application by pressing into the existing natural pavement. The article presents the results of laboratory tests demonstrating that material in question is load-resistant and chemical-resistant, while field studies have confirmed that the airfield geocell made of the plastic in question improves the load carrying capacity of natural airfield pavement.

AbstractThe basis of the work was to estimate the relationship between wheel pressure and wheel pressure on the surface, and the size of the contact surface. The article presents world experience in the field and presents the theoretical basis for calculating the contact area of a wheel with the road surface. The tests were carried out for two types of tires - ASTM E-1551 and ASFT T520. The tests proved a significant influence of the wheel pressure value and wheel pressure on the surface on the obtained surface area of the wheel contact with the surface.

The assessment of the texture of airfield pavements, in addition to assessing their roughness, is a component of the broader concept of anti-skid properties, which significantly affect the safety of air operations. The roughness of the pavement directly affects the adhesion of the aircraft tire to the pavement, and the texture additionally affects the effectiveness of dynamic drainage of water from the pavement. The current standard requirements in terms of roughness and texture of airfield pavements do not distinguish the technology used. In the paper, the authors focused on the analysis of the results in terms of the texture of airfield pavements and presented the resulting conclusions in relation to whether the technology of its implementation has an impact on the texture parameter.

The article presents an innovative method that was verified in the field. It is aimed to improve the load bearing capacity of airfield pavements, which are one of the elements of the flight safety system. Airfield pavements protect the runway in case when the aircraft is taxiing beyond the runway. Moreover, they are also used to perform starting and landing operations of military aircraft. Due to this, they need to have an adequate load bearing capacity that ensures the safety of performing aircraft flights. Airports cannot afford to be shut down for a long time; thus, it is essential to look for efficient and fast solutions that could improve the load bearing capacity of airfield pavements. The authors suggested to apply geogrid immersed in natural airfield pavement.