Trypanosomiasis caused by Trypanosoma evansi can seriously affect both domestic and wild animals. This article reports on an outbreak of canine trypanosomiasis on a farm in the Pantanal region of Brazil. The farm had 38 dogs, 20 of which died before receiving veterinary care. The remaining 18 dogs were underwent anamnesisn, clinical examination, hematological and biochemical evaluations. Blood smears and PCR analysis were performed for the diagnosis. The treatment protocols used according to the clinical recovery or parasitological cure of the dogs, using diminazene diaceturate, isometamidium chloride or quinapyramine sulfate. Post-treatment parasitological evaluation was performed by the microhematocrit technique. 7/18 dogs were PCR positive for T. evansi (confirmed by sequencing). There was clinical findings, which were consistent with both the acute and chronic stages of the disease in dogs. The infected dogs all exhibited at least one clinical sign of the disease. The hematological findings were compatible with trypanosomiasis, highlighting the hypochromic microcytic anemia as the main outcome. No treatment protocol was fully effective and the prolonged use of diminazene diaceturate caused the death of an animal. The trypanosomiasis can cause high rates of morbidity and mortality in dogs and difficulty in establishment an effective and safe therapeutic protocol.

RESUMO.As lesões no miocárdio são de difícil diagnóstico e podem ser confundidas com outras enfermidades, portanto é importante a associação de diferentes métodos de diagnósticos para a conclusão. Na medicina humana as troponinas são reconhecidas, há vários anos, como biomarcadores sensíveis e específicos na identificação de lesões miocárdica. As troponinas são expressas exclusivamente pelo miocárdio e liberadas para circulação logo após uma injúria no músculo cardíaco. Essa revisão aborda os diferentes tipos de troponinas, dando enfoque a sua aplicabilidade e comportamento como marcador de lesão tecidual em animais. Constatou-se se que o uso da troponina I cardíaca (cTnI), como biomarcador de injuria cardíaca, foi validada para o uso diagnóstico em diferentes espécies animais e é capaz de colaborar no diagnóstico e prognóstico das enfermidades miocárdicas, embora, não determinem o mecanismo da lesão. Palavras chave. Animais, biomarcadores, cTnI, isoformas cardíacas, miocárdioTroponin, a cardiac injury biomarker, in veterinary medicine: Review ABSTRACT. Lesions in the myocardium are difficult to diagnose and can be confused with other illnesses, so it is important to combine several diagnostic methods for accuracy. In human medicine, troponins have been recognized for several years as sensitive and specific biomarkers for the identification of myocardial injury. Troponins are exclusively expressed by cardiac myocytes and released into the circulation after an injury to the heart muscle. This review different types of troponins, focusing on their applicability and behavior as a marker of cardiac injury in animals. It was found that the use of cardiac troponin I (cTnI) as a biomarker of cardiac injury has been validated for diagnostic use in several animal species and can assist in diagnosis and prognostication of myocardial diseases though, but does not specify the mechanism of injury.

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O objetivo com este estudo foi estabelecer os intervalos de referências de diferentes analitos em líquido peritoneal de bovinos da raça nelore. Foram coletadas amostras do líquido de 50 machos e 50 fêmeas, oriundo de um abatedouro frigorífico na região central do Brasil. A determinação das concentrações de albumina; cálcio total; Cloro; fosfatase alcalina; glicose; Potássio; Lactato; Sódio; proteína total foi realizada em equipamento automático. Valores como razão A:G: razão albumina:globulina foram realizados por meio de cálculo matemático. Este é a primeira descrição do intervalo de referência de líquido peritoneal em bovinos da raça nelore. O tamanho da amostra e a distribuição dos dados indicam que os valores médios obtidos são representativos e podem ser usados para o diagnóstico de enfermidades nesse estrato populacional.

Here we present two cases of albinism in giant anteaters from the same area in Central Brazil. The two juvenile individuals presented light-colored fur, unpigmented eyes, and pinkish skin around the eyes, ears, and snout tip. One of the individuals died before achieving adulthood. Given that albinism might affect individual behavior, survival, and fitness, we have started the GPS monitoring of one of the albino individuals. We present the results of our initial health assessment of the individual, showing that its parameters are generally within normality. We also present opportunistic observations showing that its atypical coloration did not affect intraspecific interactions, i.e. the parental care provided by its mother. Finally, we discussthe potential relationship between the individuals, how this could be related to landscape degradation and its associations with population declines in the region. Hence, these records provide additional evidence on the urgency of implementation of conservation measures to cease further population declines of giant anteaters in the Cerrado biome, here, focusing on the Mato Grosso do Sul state, Brazil.