Cleidocranial dysplasia (CCD) it is an autosomal dominant skeletal dysplasia caused by mutation in CBFA1 (Core Binding Factor Alpha), a member of runt family of transcription factors mapped to chromosome 6p21. Radiographic images are important tools for the diagnosis of CCD. On dental radiographs, it is possible to observe 2 features of the classical triad of CCD: multiple supernumerary teeth; and open sutures and fontanelles of the skull. Third important feature hypoplasia of clavicles need additional chest radiograph. Most of mid-facial features of this syndrome can be visualized on CBCT images which save patient from exposure to different views of 2 dimensional imaging required to see widespread involvement of skull but also help in treatment planning for missing permanent teeth including accurate study of the morphology, location, alignment, proximity of teeth to structures like inferior alveolar canal and maxillary sinus well as the quality and quantity of basal bone available which could help a great deal in orthodontic planning, surgical extraction and prosthetic rehabilitation. Considering its valuable importance, CBCT is advisable in all such syndromes with multiple impacted teeth for diagnosis and treatment planning.

Background: Intellectual Disability (ID) is often associated with varied behavioural problems that have a significant emotional and social impact on both the child and parents. Objective: To identify the indications of homeopathic medicines in the treatment of behavioural problems of children with ID, using 'Lectures on Homeopathic Materia Medica by Dr. J.T. Kent', and to assess the changes on the standardized scales. Materials and Methods: A prospective, observational study was conducted on children aged 3 to 18 years with Intellectual disability. A total of 33 cases were assessed using BASIC MR PART B and WHODAS CY scales. The data was recorded and statistically analyzed. Results: Clinical indications of 17 remedies were obtained from Kent's Materia Medica, according to the totality of symptoms and the key indications obtained and used as prescriptions. Stramonium was prescribed in maximum cases (n=5). Changes in behaviour and disability were moderate in most cases and statistically significant for majority of cases. Conclusion: Medicines selected from 'Lectures on Homeopathic Materia Medica by Dr. J.T. Kent' proved to be effective in managing behavioural problems of children with ID along with the changes on overall disability levels and gave some very reliable indications for remedy prescription. Significant changes were observed in all domains of both scales. Controlled trials are warranted.

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Introduction: The presence of heavy metals in higher  quantity is a cause for concern in herbal medicines.  Around 60-70% of homoeopathic medicines are  manufactured using herbs. Herbs account for even  more than 90% of the frequently used mother  tinctures. There is a possibility of heavy metals  transfer from herbs to the mother tincture during the  manufacturing process.   Objective: This study was conducted to find out the  transmission of heavy metals from herbs to mother  tinctures.  Material and methods: 10 herbs have been identified  based on the literature survey for the presence of  heavy metals (lead, mercury, arsenic and cadmium).  Samples of both herbs and the mother tinctures made  from them have been studied for the presence of  heavy metals in mg/kg.  Results & discussion: 8 out of 10 herbs were  found to contain heavy metals. However, none of  the homoeopathic mother tinctures prepared from  these herbs has any trace of the presence of heavy  metal. Even though mother tinctures are diluted 10  times and they may contain 1/10th of heavy metals  present in the herbs, we could not find even 1/10th of the heavy metal in the mother tincture. This could  be due to their insoluble nature in the solvents used.  Perhaps all the heavy metals have been retained into  the herbal residue.  Conclusion: Heavy metals present in the studied  herbs do not transport during the manufacturing  of homoeopathic mother tinctures. Thus, these  homoeopathic mother tinctures may be considered  safe with respect to heavy metals.

Background: Hair loss, or alopecia, is a common  disorder that affects between 0.2-2% of the world's  population and have significant impacts on a person's  mental and physical health. Normal hair loss on  a healthy head is between 50 and 100 hairs a day.  Alopecia is a disorder in which the follicles in certain  people start losing hair prematurely because they are  not healthy, increasing the pace at which hair falls.  Alopecia can be caused by poor nutrition, chronic  stress, genetics, or other factors, and there are several  types, each with a unique cause and symptom. Apart  from improving quality of life, using methods like hair  treatments or transplants, many homeopathic herbal  ingredients are reported useful in managing alopecia  and hair fall. This study was aimed to investigate the  effectiveness of a formulation Zauberӧl® containing  Arnica montana, Ceanothus americanus, Eclipta  prostrata, Hibiscus Rosa sinensis, Jaborandi, Murraya  koenigii, Sabal serrulata & Thuja occidentalis in  testosterone-induced alopecia in Wistar rats.