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Total 50 indoor HIV positive patients clinically suspected of having tuberculous lymphadenitis were included by purposive sampling method. Information regarding past and family history were collected after taking written consent using pre designed, pretested semi structured Performa. Patient were examined and evaluated by necessary investigation. Data was statistically analysed using SPSS software (trial version). Results: Out of total 50 patients, 42 (84%) patients were male. Age range of patients was 11 to 70 years with mean age was 34.8 ±10.3 years. All 50 patients presented with painless swelling. 11 (22%) patients had past history and 3 (6%) had family history of tuberculosis. 47 (94%) patients had cervical lymphadenopathy. 5 (10%) had sputum positive pulmonary tuberculosis. 21 (42%) patients were already on anti-retro viral therapy (ART). 23 (46%) patients had epithelioid granuloma with necrosis followed by 18 (36%) patients had epithelioid granuloma without necrosis revealed by FNAC. Half of the patients had abnormal chest radiograph with infiltration and pleural effusion in 14% and 10% respectively. Conclusions: Cervical and axillary lymphadenopathy was most common involved site in tuberculous lymphadenitis in HIV positive patients. FNAC is a relatively inexpensive initial investigative technique in the diagnosis and management of HIV-positive patients.

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