Dwindling supplies of fossil fuels and their deleterious impacts on human health and the global environment have intensified the search for substitute energy sources. Biodiesel has been identified as a promising renewable energy substitute for diesel fuel due to several comparable and sustainable properties. However, approximately 95% of biodiesel is derived from edible oil crops, threatening the current food supplies. Therefore, the biodiesel production potential from inexpensive, non-edible, and non-conventional bioenergy crops, such as Jatropha (Jatropha curcas L.), has attracted the attention of many researchers, policymakers, and industries globally. Jatropha is considered to be the second-generation biofuel feedstocks for biodiesel production. However, sustainable biodiesel generation from J. curcas oil has not yet been attained, owing to different socio-economic, ecological, and technical factors. This study aimed to synthesize the information from the existing literature on the present status and to identify the knowledge gaps for future research on Jatropha by providing comprehensive information regarding its origin and distribution, morphology, phenology, and reproduction, genetic diversity, its productivity, oil content, and fatty acid composition, the methodology used for extracting biodiesel, and agronomic, economic, and environmental aspects of biodiesel production. The germplasm screening of J. curcas and the exploration of its adaptability and agronomic potential across diverse climates are highly desired to promote this crop as an alternative biofuel crop, particularly in arid and semi-arid regions. Moreover, future research should focus on developing, optimizing, and modernizing the technologies involving seed collection, the processing of seeds, oil extraction, and the production of biodiesel.

Climate prediction models suggest that agricultural productivity will be significantly affected in the future. The expected rise in average global temperature due to the higher release of greenhouse gases (GHGs) into the atmosphere and increased depletion of water resources with enhanced climate variability will be a serious threat to world food security. Moreover, there is an increase in the frequency and severity of long-lasting drought events over 1/3rd of the global landmass and five times increase in water demand deficits during the 21st century. The top three cereals, wheat (Triticum aestivum), maize (Zea mays), and rice (Oryza sativa), are the major and staple food crops of most people across the world. To meet the food demand of the ever-increasing population, which is expected to increase by over 9 billion by 2050, there is a dire need to increase cereal production by approximately 70%. However, we have observed a dramatic decrease in area of fertile and arable land to grow these crops. This trend is likely to increase in the future. Therefore, this review article provides an extensive review on recent and future projected area and production, the growth requirements and greenhouse gas emissions and global warming potential of the top three cereal crops, the effects of climate change on their yields, and the morphological, physiological, biochemical, and hormonal responses of plants to drought. We also discuss the potential strategies to tackle the effects of climate change and increase yields. These strategies include integrated conventional and modern molecular techniques and genomic approach, the implementation of agronomic best management (ABM) practices, and growing climate resilient cereal crops, such as millets. Millets are less resource-intensive crops and release a lower amount of greenhouse gases compared to other cereals. Therefore, millets can be the potential next-generation crops for research to explore the climate-resilient traits and use the information for the improvement of major cereals.

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Background: Japanese encephalitis (JE) is one of the major public health problems particularly in the Terai regions of Nepal. Children upto the age of 15 years are more susceptible for JE. The present study was conducted to aim the sero-prevalence of JE among children of Nepal. Methods: The samples were collected and processed at National Public Health Laboratory (NPHL). In this study, children of age upto 15 years defined with Acute Encephalitis Syndrome (AES) were studied. A total 1009 samples, were collected and tested by MAC ELISA technique for the detection of Anti JEV-IgM. Results: From the processed samples, 107 (10.61%) were found positive for Anti JEV-IgM. Among

Methodologies are proposed to develop criteria for classifying geomaterials into soils, intermediate geomaterials (IGMs), and hard rocks to achieve efficient driven pile designs. IGMs were categorized into IGM-soils and IGM-rocks to reduce the uncertainties in pile resistance estimations associated with properties ranging from soils to rocks. A boundary between soils and IGM-soils was established based upon the performance of two static analysis methods measured in terms of the coefficients of variation between measured and estimated shaft resistances. A boundary between IGM-rocks and hard rocks was established by limiting the geotechnical resistance in IGM-rocks to the compressive strength of a steel pile. Finally, a geomaterial classification flowchart and sample design charts are proposed to facilitate the classification of geomaterials specifically for the design and construction of driven steel H-piles. The proposed framework can be adapted for other driven pile types.