Synthesis of α-Aminophosphonates at Room Temperature. -The simple three--component process allows an access to various title compounds as analogues of amino acids in good to excellent yields. The use of ketones instead of aldehydes is unsuccessful. -(DAR, B.; SINGH, A.; SAHU, A.; PATIDAR, P.; CHAKRABORTY, A.; SHARMA, M.; SINGH*, B.; Tetrahedron Lett. 53 (2012) 41, 5497-5502, http://dx.
Clays revealed high catalytic activity for the synthesis of a series of substituted 2, 3-dihydro-2-phenylquinazolin-4(1H)-one. The synthesis was carried out by reacting Anthranilamide and various substituted aldehydes in acetonitrile at roo m temperature in the presence of a small amount of the catalyst. Several solvents were examined for this reaction; however, in terms of reaction yield and time, Acetonitrile was found to be the optimu m solvent.
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