No abstract

It is a rare neurogenic illeness; because of its clinical characteristics it is important for dentists. PWS is first know human genomic imprinting disorder, microdeletion syndrome. It is caused by the absence of certain paternally inherited genes on long arm of chromosome 15. The clinical picture of Prader-Willi syndrome is complex and alters with age. It is mostly due to impaired hypothalamus function. The characteristic features include short stature; muscular hypotonia; hypopigmentation of the skin and hair; a triangular facies, frequently with a small mouth with a thin upper lip and down-turned corners; and diminished secretion of thick and sticky saliva. The article describes the phenotypic features of Prader-Willi syndrome (PWS) and their impact on the oral health status Primary care by pediatric dentist's play an important role in children's with PWS.

Physiology of a child is much different from an adult and a child should not be considered a small-sized adult. They have different developmental pharmacokinetics due to which they are more sensitive to drug effects. This has led to the adoption of new dental materials derived from natural origin instead of conventional chemicals to reduce the side effects and complications. Propolis is one such natural substance that is widely used for various clinical trials in dentistry and has shown very promising results. Due to its anti-inflammatory, anticariogenic, and immunomodulating effects, it has now become quite familiar material in dental applications. It is eco-friendly, economical, complications free, easily available, and easy to use in daily dental practices. Hence, it has opened a new field of research and analysis for scientists and researchers.