<p class="Default"><strong><em>Introduction</em></strong><em>: Cardiovascular disease (CVD) is a major cause of death and disability worldwide. The most stringent primary CVD screening guidelines in developed countries use absolute CVD risk scores or coronary heart disease, such as Framingham or SCORE (Systematic Coronary Risk Evaluation) there are two types of CVD risk factors namely modifiable risk factors and unmodified risk factors. <strong>The aim</strong> of the current study is to determine the profil of potentially modifiable and unmodified cardiovascular risk factors. <strong>Method</strong>: </em><em>This research consists of 41 elderly people which aged ≥ 60 years in Guguak, Kabupaten 50 Kota, West Sumatera, Indonesia. The data taken is modifiable risk factors consisting of diseases related risk factors </em><em>including blood pressure categories, lipid profile, central obesity, body mass index </em><em>and lifestyle related risk factors such as </em><em>smoking habit</em><em>. We also take data of unmodified risk factors such as age and gender</em><em>. <strong>The result</strong>: t</em><em>his study consists of 41 elderly people which aged ≥ 60 years in Guguak, Kabupaten 50 Kota, West Sumatera, Indonesia. The mean age of elderly were 68</em><em>±</em><em>7.64861 years old that consisting of 29.3% men and 70.7% women, </em><em>34% of elderly with hypertension, the elderly with hypercholesterolemia 71%, hypertriglyceridemia 41%, and the elderly women with low HDL-C levels were 53%, the elderly men with low HDL-C levels were 92%. <strong>Conclusion</strong><strong>: </strong>There are two types of risk factors CVD, modifiable risk factors and nonmodifiable risk factors. </em><em>The modifiable risk factors consisting of diseases related risk factors </em><em>including blood pressure categories, lipid profile, central obesity, body mass index </em><em>and lifestyle related risk factors such as </em><em>smoking habit.</em></p>
Chronic Kidney Disease (CKD) is a very common clinical problem in elderly patients and is associated with increased morbidity and mortality. The proportion of the elderly is predicted to further rise to 20% by the year 2030 caused by the demographic change from a pattern of high birth rates and high mortality to low birth rates. Delayed mortality has contributed to the rise in the elderly population. The aging process involves physiological and nutritional changes that will affect the nutritional status of the elderly, leading to malnutrition and overweight. Aging is associated with considerable changes in body composition, higher BMI is associated with improved survival in patients with CKD and very low BMI levels have been consistently associated with high all-cause mortality in the elderly. The changes in Body Fat Percentage (BFP) in the elderly will affect the estimated Glomerular Filtration Rate (eGFR) in the elderly. This study aimed to determine the correlation between anthropometric measurement and kidney function in the elderly population. this research is an analytic observational study with a cross-sectional design, which involved 42 elderly people with age > 60 years in Guguak District, West Sumatera, Indonesia. Anthropometric measurement using the Waist-to-Height-Ratio (WHtR) method, Waist-to-Hip Ratio (WHR), Waist Circumference (WC), and Body Mass Index (BMI) and eGFR were calculated using the Cockcroft and Gault formula. The results of this study showed that the mean age of the elderly was 68±7.58 years, which consisted of 29.3% male and 70.7% female. The Pearson correlation test between WHR and eGFR obtained p<0.05 with r= 0.439 and the Pearson’s correlation test between BMI and eGFR obtained p<0.05 with r= 0.425. There was a moderate correlation between WHR with eGFR and BMI with eGFR in the elderly population.
Hepatocellular carcinoma (HCC) is a malignant tumor derived from hepatocyte cells including primary malignant epithelial tumors. Hepatocellular carcinoma is the second most common cause of cancer-related deaths worldwide, and events are expected to increase in the future and the incidence of HCC will continue to increase until 2030. Early detection of HCC is very important to improve prognosis and long-term survival. late detection of HCC and lack of care. This study aims to determine serum AFP levels in HCC patients in DR. M. Djamil Hospital, Padang, West Sumatra, Indonesia. This research is a descriptive study, which consisted of 30 serum samples of HCC patients. The examination method is Enzyme Linked Fluorescent Assay (ELFA). In this study, the incidence of hepatocellular carcinoma in men was higher than in women. For both sexes, the incidence of HCC increases with ages between 26-60 years. The increased presence of AFP can alert doctors to the possibility of a diagnosis of HCC. Keywords: Alpha fetoprotein serum, Hepatocelular carcinoma, West Sumatera, Indonesia
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