Objective: To compare the reduction of plaque and gingivitis from the following three toothpaste formulations containing: 0.3% Triclosan, 1,000ppm fluoride and 0.13% calcium glycerophosphate in a natural calcium carbonate base (a new paste); 0.2% Triclosan and 1,000ppm fluoride in a precipitated calcium carbonate base; 0.3% Triclosan, 1,000ppm fluoride and Gantrez in a silica base. A control group was maintained, which used commercially available toothpastes without the above actives. Methods: A double‐blind, four‐cell, stratified, parallel group design study. Subjects brushed twice daily with their allocated toothpaste for 12 weeks. Plaque, MGI and gingival bleeding assessments were carried out at baseline, after 6 and 12 weeks of product use. Results and conclusion: An analysis of covariance of the 12‐week results showed significant differences between products [p<0.0001] for plaque, MGI and gingival bleeding. The new toothpaste formulation containing 0.3% Triclosan, 1,000ppm fluoride and 0.13% calcium glycerophosphate in a natural calcium carbonate base was shown to be significantly more effective in reducing plaque and gingivitis than the other toothpaste formulations in the study.
The difficulty in diagnosis and the need for a search for acid-and alcohol-fast organisms in adequate biopsy material are re-emphasized.With the use of antituberculous drugs, the results of surgical treatment in all but the ulcerative type are satisfactory, and resection, though desirable, is not mandatory.Ulcerative intestinal tuberculosis remains a very dangerous condition, and the only hope of improvement in outcome appears to lie in active drug therapy on suspicion, and in improvements in the control of tuberculosis generally.Acknowledgements.-We would like to record our thanks to the medical and surgical staff of the
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