A series of 3-[2-chloroquinolin-3-yl)methylene]-5-aryl-furan-2(3H)-ones {3(a-p)} were synthesized. The required 3-(substitutedbenzoyl) propionic acids {2(a-d)} were prepared under Friedal Craft acylation reaction conditions. The substituted 2-chloroquinoline-3-carbaldehydes {1(a-d)} were synthesized by reaction of substitutedphenylethanone-oxime with phosphorus oxychloride in presence of dimethyl formamide using the Vilsmeir Haack reaction method. These compounds were screened for their anti-inflammatory and antibacterial activities along with their ulcerogenic and lipid peroxidation potentials. The compounds that showed significant anti-inflammatory activity were further screened for their analgesic activity. The compounds were less toxic in terms of ulcerogenicity as compared to a standard, which was also supported by lipid peroxidation studies. The antibacterial activities were performed against Staphylococcus aureus and Escherichia coli. Compounds 3f, 3n and 3o showed significant activity against both S. aureus and E. coli having an MIC value of 6.25μg mL-1

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The Ad-Hoc on demand distance vector (AODV) routing protocol to be used by mobile nodes in an ad hoc network. It offers fast adaptation to dynamic link conditions, low process and memory overhead, low network utilization and determines unicast routes destinations inside the ad hoc network. It uses destination sequence numbers to confirm loop freedom in any respect of times (even within the face of abnormal delivery of routing management messages), avoiding issues (such as "continuity to infinity") related to classical distance vector protocols. Ad-Hoc networking could be a thought in pc communications characterized by property through a set of wireless nodes and fast changing network topology. In a wireless scenario, nodes are free to move hence maintaining path (route) is a difficult task. Routing protocols have central role in a wireless scenario. We have analyzed AODV protocol by extensive simulations in ns-2 simulator with various performance matrices such as Throughput, Number of packets sent, Number of packets received, Packets delivery ratio, Control overhead, Packet dropping ratio, Delay, Normalized routing overhead under wireless scenarios varying speed. And with this we are also trying to detect the Black Hole Attack in AODV.

The axisymmetric steady flow of a couple stress fluid between two concentric cylinders with a slip effect is investigated with the help of the cell model technique. Here, the inner cylinder is rigid, and the outer cylinder is fictitious. The tangential slip, vanishing of normal velocity, and zero couple stress conditions are applied on the inner cylindrical surface. In addition, zero shear stress (Happel's model), continuity of normal velocity component, and zero couple stress conditions are used on the outer cylindrical surface. We consider two flow problems: the first is the parallel flow, and the second is the perpendicular flow to the cylinder in the cell model. Also, we have discussed the random case. For all the cases, the Kozeny constant is calculated. We described some special cases and compared them with well-known results. The effects of slip and couple stress parameters on the Kozeny constant with fixed value of couple stress viscosity parameter are presented graphically. The influence of the couple stress viscosity parameter on the Kozeny constant with fixed values of couple stress, and slip parameters for parallel flow are expressed graphically. The numerical values for the Kozeny constant for different values of fractional void volume are tabulated. We also obtained the results of the consistent couple stress theory as a special case.

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