Background: External beam radiotherapy (EBRT) is mainstay of treatment in pa ents with locally advanced cervical carcinoma (LACC). Three dimensional conformal radiotherapy (3DCRT) and intensity modulated radiotherapy (IMRT) are mainly used in EBRT. However which one is superior is s ll controversial. Materials and Methods: Forty pa ents of LACC treated with IMRT were selected for this study. 3DCRT plans were also created for all the pa ents. 3DCRT and IMRT plans were compared on the basis of planning target volume (PTV) coverage, dose to normal organs, homogeneity index (HI) and conformity index (CI 95% ). Results: In both the techniques 99% of PTV was covered with more than 96% of prescribed dose (PD). D 15, D 35 and D 50 (Dose to 15%, 35% and 50% volume respec vely) for bladder was reduced by 2.09%, 14.623% and 32.57% and for the rectum it was reduced by 7.46% ,23.82% and 43.68% in IMRT compared to 3DCRT. V 45 (volume receiving 45 Gy) in case of bowel were found to be much less in IMRT in comparison to 3DCRT. Insignificant difference found between doses to femoral heads in IMRT and 3DCRT. The CI 95% in IMRT plans was found much be:er than that in 3DCRT whereas HI in both the techniques were found almost same. Conclusion: IMRT significantly reduced the irradiated volume of OAR and improved dose conformity in the PTV compared to that by 3DCRT. So, it can be concluded that IMRT should be chosen as preferred technique for the EBRT of LACC with proper immobilizing devices and imaging.

Background: For chest wall irradiation in breast cancer patients, three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) have made tremendous changes in treatment delivery.

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Quality assurance (QA) before patient treatment plays a major role in complex radiotherapy (RT) treatment planning. Phantoms are the standard materials that are used for the pre-treatment QA of patients. Contemporary phantoms used in RT are mainly water-based, having simple geometry and of uniform density. These phantoms dose not replicate the exact heterogeneities of the actual human body. The present work aims to evaluate the results of relative dosimetry performed on in-house developed heterogeneous thorax phantom (HTP) using an electronic portal imaging device (EPID). To perform the relative dosimetry, contours were drawn on HTP at three different locations and intensity modulated radiotherapy (IMRT), as well as Rapid ARC (RA), were generated on it to compare the fluence obtained on TPS as well as on linac machine. The gamma evaluation results indicate a strong correlation between planned and the measured fluence. We found the EPID-based QA done on HTP explore its property as a QA tool and it can further be used to perform patient-specific relative dosimetry.

The target coverage and doses to organs at risk (OARs) were achieved as per the ABS guidelines. Hence, it can be concluded that the Co-60 HDR brachytherapy unit is a good choice especially for the centers with a small number of brachytherapy procedures as no frequent source replacement is required like in an Ir-192 HDR unit.