PRP is a potentially useful substance in the fight against periodontal pathogens. This might represent a valuable property in adjunct to the enhancement of tissue regeneration.

:The successful replacement of lost natural teeth by tooth root analogues is a major advancement in the field of dentistry. The success greatly depends on adequate integration of these implants within the bone. This bone-implant integration is known as osseointegration. The science of osseointegration has widened the scope of treatment options for edentulous patients.

Dermatoglyphics can lead to early diagnosis, treatment, and better prevention of many genetic disorders of the oral cavity and other diseases whose etiology may be influenced directly or indirectly by genetic inheritance.

Periodontitis is a multi-factorial disease which has affected mankind since the dawn of an era. Prevalence of periodontal disease has considerably increased over a period of time. Periodontal research has progressed tremendously worldwide. In India in spite of increased periodontal research, many problems are faced by the clinicians. It leads to improper recording of the results and resultant failure to spread the knowledge that would help in understanding the subject better. This is a major setback in the current era of evidenced based clinical practice. Hence in this review, an attempt is made to discuss and emphasize these unsolved issues pertaining to epidemiology, disease activity and therapy.