Neonatal sepsis is a clinical syndrome characterized by symptoms of bacteremia and systemic signs and positive blood cultures showed that during the first month of life. Prematurity and postmaturity risk of morbidity and mortality are high on the gestation age for the occurrence of neonatal sepsis. This study aims to determine the relationship between gestational age and the incidence of neonatal sepsis in Ulin Hospital Banjarmasin. The design of this study using cross sectional study with retrospective approach. The way the sampling is the purposive sampling were obtained from medical records of patients, then performed statistical analysis using chi-square test with 95%. The number of samples that fulfilled the criteria inclusion in this study as many as 246 cases. The incidence of neonatal sepsis is more common in infants born at 37-42 weeks gestation as many as 25 cases (59.52%). The data not neonatal sepsis who were born with a gestational age <37 weeks or> 42 weeks gained as many as 20 cases (9.80%) and 37-42 weeks gestation obtained as many as 184 cases (90.20%). Chi-square test showed that there is a relationship between gestational age and the incidence of neonatal sepsis in Ulin Hospital Banjarmasin (p = 0.000) with an odds ratio (OR) 6.256. It is concluded that there is a relationship of gestation age and the incidence of neonatal sepsis (p <0.05) in hospitals Ulin Banjarmasin period June 2014-June 2015 with OR 6.256. Keywords: gestational age, sepsis, neonatal Abstrak: Sepsis neonatorum merupakan suatu sindrom klinis bakteremia yang ditandai dengan gejala dan tanda sistemik serta menunjukkan kultur darah positif yang terjadi pada bulan pertama kehidupan. Prematuritas dan posmaturitas memiliki risiko kesakitan dan kematian yang tinggi pada masa gestasi untuk terjadinya sepsis neonatorum. Penelitian ini bertujuan untuk mengetahui hubungan antara masa gestasi dan kejadian sepsis neonatorum di RSUD Ulin Banjarmasin. Rancangan penelitian ini menggunakan cross sectional study dengan pendekatan retrospektif. Cara pengambilan sampel yaitu dengan purposive sampling yang diperoleh dari data rekam medis pasien, kemudian dilakukan analisis statistik menggunakan uji chi-square dengan kepercayaan 95%. Jumlah sampel yang memenuhi kriteria inklusi dalam penelitian ini sebanyak 246 kasus. Kejadian sepsis neonatorum lebih banyak dijumpai pada bayi yang lahir dengan masa gestasi 37-42 minggu yaitu sebanyak 25 kasus (59,52%). Data neonatus tidak sepsis yang lahir dengan masa gestasi <37 minggu atau >42 minggu didapatkan sebanyak 20 kasus (9,80%) dan masa gestasi 37-42 minggu didapatkan sebanyak 184 kasus (90,20%). Uji chi square menunjukkan bahwa terdapat hubungan antara masa gestasi dan kejadian sepsis neonatorum di RSUD Ulin Banjarmasin (p=0,000) dengan odds ratio (OR) 6,256. Kesimpulan penelitian ini adalah terdapat hubungan masa gestasi dan kejadian sepsis neonatorum (p<0,05) di RSUD Ulin Banjarmasin periode Juni 2014-Juni 2015 dengan OR 6,256. Kata-kata kunci: masa gestasi, sepsis, neonatus
BackgroundFerritin has been recognized as a predictor of severity among Coronavirus-19 disease (COVID-19) patients. Studies have shown higher levels of ferritin in patients with COVID-19 than in healthy children. Patients with transfusion-dependent thalassemia (TDT) basically have high ferritin level due to iron overload. It is uncertain whether serum ferritin level in these patients is associated with COVID-19 infection.ObjectiveTo evaluate ferritin levels in TDT with COVID-19 before, during, and after the course of infection.MethodsThis retrospective study enrolled all TDT children with COVID-19 infection that were hospitalized in Ulin General Hospital Banjarmasin during the COVID-19 pandemic (March 2020 to June 2022). Data were collected from medical records.ResultsThere were 14 patients included in this study, 5 patients had mild symptoms and 9 patients were asymptomatic. The mean of hemoglobin level upon admission was 8.1 ± 3 g/dL and serum ferritin level were 5148.5 ± 2651.8 ng/mL. The average serum ferritin level during COVID-19 infection was 2373.2 ng/mL higher than before infection and then decreased by 952.4 ng/mL after infection. We found no association of increasing serum ferritin with patients’ symptoms (p = 0.27). The severity of anemia also was not correlated with the presentation of COVID-19 infection (p = 0.902).ConclusionSerum ferritin levels in TDT children may not reflect disease severity or predict poor outcomes during COVID-19 infection. However, the presence of other co-morbid conditions/confounders warrants cautious interpretation.
Abstract:Neonatal asphyxia is a condition where the baby can not breathe spontaneously and regularly soon after birth or shortly after birth. Birth weight is a part of the factors that can cause neonatal asphyxia. Research conducted retrospective observational analytic approach to determine the relationship between birth weight and neonatal asphyxia which uses secondary data from medical records of patients. The study was conducted in August-October 2015 in the NICU and medical record room of RSUD Ulin Banjarmasin. The sampling technique used purposive sampling and obtained a sample of 334 cases. The statistical test used is chi-square test with 95% confidence level. The results showed that of 334 cases of birth weight data showed 17.4% risk birth weight and no-risk birth weight by 82,6%. Neonatal asphyxia 26.3% and 73.7% of no-neonatal asphyxia. Based on the statistical test showed p = 0.674 so that it can be concluded that there is no significant correlation between birth weight and neonatal asphyxia in RSUD Ulin Banjarmasin period June 2014-June 2015.Keywords: neonatal asphyxia, birth weight, risk factor Abstrak: Asfiksia neonatorum adalah suatu keadaan dimana bayi tidak dapat bernapas secara spontan dan teratur segera setelah lahir atau beberapa saat setelah lahir. Berat badan lahir merupakan bagian dari faktor neonatus yang dapat menyebabkan asfiksia neonatorum. Penelitian dilakukan secara observasional analitik dengan pendekatan retrospektif untuk mengetahui hubungan antara berat badan lahir dan kejadian asfiksia neonatorum yang menggunakan data sekunder dari rekam medis pasien. Penelitian dilakukan pada bulan Agustus-Oktober 2015 di ruang NICU dan ruang rekam medis RSUD Ulin Banjarmasin. Teknik pengambilan sampel menggunakan metode purposive sampling dan didapatkan sampel sebanyak 334 kasus. Uji statistik yang digunakan yaitu uji chi-square dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa dari 334 kasus diperoleh data berat badan lahir berisiko sebesar 17,4% dan berat badan lahir tidak berisiko sebesar 82,6%. Kejadian asfiksia neonatorum sebesar 26,3% dan tidak asfiksia neonatorum sebesar 73,7%. Berdasarkan hasil uji statistik didapatkan hasil p = 0,674 sehingga dapat disimpulkan bahwa tidak terdapat hubungan yang bermakna antara berat badan lahir dan kejadian asfiksia neonatorum di RSUD Ulin Banjarmasin periode Juni 2014-Juni 2015. Kata-kata kunci: asfiksia neonatorum, berat badan lahir, faktor risiko
Preeclampsia is a serious complication of pregnancy and occurs in 3-8% of all pregnancies. Preeclampsia can affect newborn, causing hypoxia, Intra Uterine Growth Retardation, preterm labor and low birth weight babies (LBW). Pregnant women are easily infected by SARS-CoV-2. Fetal complications of mothers that infected with COVID-19 include miscarried, IUGR, and preterm birth. Preeclampsia can be exacerbated or exacerbate by COVID-19 which has an impact of the condition of the newborn. The purpose of this study was to determine difference of neonatal outcomes of preeclampsia mothers with COVID-19 and without COVID-19 at Ulin Hospital Banjarmasin for the period May 2020-April 2021. This study was an analytical observational study with a retrospective approach used the Chi-square test and Fisher's exact test as an alternative. The data used was from medical records. The sample used was neonates born to preeclampsia mothers with COVID-19 and without COVID-19 at Ulin Hospital Banjarmasin for the period May 2020-April 2021, selected by purposive sampling and met the inclusion and exclusion criteria. The results showed a significant difference of the outcome of the length of stay of neonates (p= 0.002) and no significant difference of the outcomes of neonates with low birth weight (p= 0.271), preterm (p= 0.126), the 1st minute (p= 0.731) and 5th minute (p= 0.993) of APGAR score, and mortality (p= 0.240). The conclusion of this study is there was only a difference in the length of stay while the other outcomes did not. Keywords: neonatal outcome, preeclampsia, COVID-19 Abstrak: Preeklamsia merupakan komplikasi kehamilan berat dan terjadi sekitar 3-8% dari keseluruhan kehamilan. Preeklampsia dapat berpengaruh terhadap bayi yang dilahirkan, menyebabkan hipoksia, pertumbuhan janin terhambat, persalinan prematur dan bayi berat lahir rendah (BBLR). Ibu hamil mudah terinfeksi oleh SARS-CoV-2. Komplikasi janin pada ibu yang terinfeksi COVID-19 berupa keguguran, IUGR, dan kelahiran prematur. Preeklampsia dapat diperburuk atau memperburuk kehamilan dengan COVID-19 yang berdampak pada kondisi bayi yang dilahirkan. Tujuan penelitian untuk mengetahui perbedaan luaran neonatal pada ibu preeklampsia dengan COVID-19 dan tanpa COVID-19 di RSUD Ulin Banjarmasin periode Mei 2020-April 2021. Penelitian berupa observasional analitik dengan pendekatan retrospektif menggunakan uji Chi-square dan Fisher’s exact test sebagai alternatif. Data yang digunakan dari rekam medik. Sampel penelitian berupa neonatus yang lahir dari ibu preeklampsia dengan COVID-19 dan tanpa COVID-19 di RSUD Ulin Banjarmasin periode Mei 2020-April 2021, dipilih secara purposive sampling dan memenuhi kriteria inklusi dan eksklusi. Hasil penelitian terdapat perbedaan bermakna (p= 0,002) pada luaran lama rawat inap neonatus dan tidak terdapat perbedaan bermakna pada luaran neonatus dengan BBLR (p= 0,271), prematur (p= 0,126), skor APGAR neonatus menit ke-1 (p= 0,731) dan ke-5 (p= 0,993), dan meninggal (p= 0,240). Kesimpulan penelitian hanya terdapat perbedaan pada luaran lama rawat inap sedangkan luaran lainnya tidak. Kata-kata kunci: luaran neonatal, preeklampsia, COVID-19
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