To study the use of 1 % isosulfan blue dye in identifying sentinel node, sensitivity and specificity of frozen section and predictive value of sentinel node in predicting other nodal status in the cases of oral cavity and oropharyngeal squamous cell carcinoma. 15 patients of oral cavity and oropharyngeal SCC with clinically N0 neck, who required WLE of the primary lesion as well as neck dissection as per recommended treatment protocol, were selected from OPD. 1 % Isosulfan dye was injected peritumorally intraoperatively after the induction of general anaesthesia. Neck dissection was performed and first node taking up the blue dye was identified, dissected, removed and was sent for frozen section. In two of the 15 cases a sentinel node was identified (sensitivity of the technique-13 %). Both the sentinel nodes were positive for presence of metastasis on final histopathology (specificity-100 %). However, five cases had nodal metastasis on final histopathological examination of the neck dissection specimen (sensitivity of sentinel lymph node biopsy-40 %). Frozen section examination had a sensitivity and specificity of 100 %. All data was analyzed using SPSS 16 software. Use of 1 % Isosulfan Dye for identification of sentinel node is a simple and cheap technique, however, it has low sensitivity as compared to the use of triple diagnostic procedure consisting of lymphoscintigraphy, per op gamma probe localization and using isosulfan dye for sentinel node identification. Sentinel lymph node is representative of nodal status and correlates well with the final histopathological examination of the dissected neck nodes.Keywords Sentinel node Á N0 neck Á Isosulfan blue dye Á Frozen section Á SLNB (sentinel lymph node biopsy)

Objective: To assess the clinical utility of a validated Hindi VHI in the assessment of patients treated microsurgically for benign vocal fold lesions. Design: Prospective study. Setting: Tertiary health care centre. Materials and Methods: The study population comprised 46 patients of either sex with benign vocal fold lesions, who underwent microlaryngeal surgery in our hospital between January, 2011 and May, 2012. An acoustic analysis of all the patients was done using Dr. Speech voice analysis software (Tiger electronics, USA) preoperatively and 6 weeks postoperatively. The parameters analyzed were in terms of perturbation (Jitter and shimmer), normalized noise energy (NNE), and fundamental frequency (F0). A validated Hindi version of VHI was filled by all the patients preoperatively and 6 weeks postoperatively. The results obtained were statistically correlated using SPSS 17 software. Results: There was a significant correlation between the parameters analyzed on Dr. Speech voice analysis software and VHI parameters obtained preoperatively and postoperatively as assessed using Pearson's correlation coefficient. There was a statistically significant improvement in objective voice parameters and VHI scores postoperatively as assessed using Pearson's correlation coefficient. Conclusion: The validated Hindi version of VHI correlates well with the widely used acoustic analysis software (Dr. Speech, Tiger electronics, USA). It also correlates well with voice improvement after surgeries for benign vocal fold lesions. It merits inclusion in the standard evaluation protocol both in the preoperative assessment and postoperative evaluation following surgical treatment for benign vocal fold lesions in Hindi speaking population.

Primary genital herpes is associated with involvement of extragenital sites like thighs, buttocks, fi ngers and pharynx. This involvement occurs due to autoinoculation, orogenital exposure from the source and also seeding due to viremia in the initial period. Involvement of larynx in a case of primary genital herpes is extremely rare prompting us to report this case.