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: Natural products have widely been used in applications ranging from antibacterial, antiviral, antifungal and various other medicinal applications. Use of these natural products was recognized way before the establishment of basic chemistry behind the disease and the chemistry of plant metabolites. After the establishment of plant chemistry various new horizons evolved, and application of the natural products breached the orthodox limitations. In one such interdisciplinary area, use of plant materials in the synthesis of nano particles (NPs) has exponentially emerged. This advancement has offered various environment friendly methods where hazardous chemicals are completely replaced by natural products in the sophisticated and hectic synthesis processes. This review is an attempt to understand the mechanism of metal nano particles synthesis using plant materials. It includes details on the role of plant’s secondary metabolites in the synthesis of nano particles including the mechanism of action. In addition, use of these nano materials has widely been discussed along with the possible mechanism behind their antimicrobial and catalytic action.

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