Background: The content of secondary metabolites in amla (phyllanthus emblica L.) such as flavonoids and phenols have the potential as an antioxidant. One of the benefits of antioxidants is to prevent degenerative diseases, such as diabetes mellitus. Purpose: This research to determine activity of amla fruit extract in reducing blood glucose levels at balb/c mice induced with alloxan. Methods. This research method uses a pre and posttest-controlled group design with 35 balb/c mice divided into five treatments groups. In the positive control group and the treatment group alloxan was injected for 14 days. Results: Amla (Phyllanthus emblica L.) fruit extract at a dose of 40 mg / 20 g BW was equivalent to positive control of glibenclamide dose 3 mg / 20 g BW compared to the treatment group at a dose of 10 mg / 20 g BW and 20 mg /20 g BW. Conclusion: From this research, it was obtained that the best dose of Amla fruit (phylanthus emblica L) extract applied to blood glucose was 40 mg/20mg BW with a decrease percentage of 56,93% with an effective dose value (ED50) 50% of 34.00 mg / 20 g BW.
Penelitian ini bertujuan untuk mengetahui efektivitas antibakteri formulasi sediaan sabun padat ekstrak bunga gemitir (Tagetes erecta L.) dan mengetahui baku mutu SNI dari sabun antibakteri yang dihasilkan. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 4 formula dan 3 kali ulangan. Formula dalam penelitian ini adalah penambahan ekstrak bunga gemitir (Tagetes erecta L.) sebesar 0; 1; 1,5; 2 %. Uji aktivitas antibakteri terhadap Staphylococcus aureus dan Escherichia coli dilakukan dengan metode difusi sumur. Sedangkan uji kualitas sabun ditentukan dengan uji organoleptis, kadar air, pH, asam lemak bebas/alkali bebas dan lemak tak tersabunkan. Hasil penelitian menunjukkan bahwa ekstrak bunga gemitir (Tagetes erecta L.) dapat diformulasikan dalam sediaan sabun padat dan menunjukkan aktivitas antibakteri dengan semua formulasi kategori sedang terhadap bakteri S. aureus dan E. coli dengan diameter zona hambat terbesar adalah formula F3 (penambahan ekstrak bunga gemitir 2%), yaitu 18,567 mm terhadap bakteri gram positif S. aureus dan 19,80 mm terhadap bakteri gram negatif E.coli. Hasil Uji kualitas sabun padat ekstrak bunga gemitir sesuai dengan standar SNI.
Tujuan: Artikel ini bertujuan untuk mengkaji pengobatan tradisional Bali, dengan mengambil fokus kajian pada pengobatan yang tertuang dalam lontar Usadha Tiwang. Metode penelitian: Penelitian ini menggunakan metode kepustakaan (Library Research). Unit analisis berupa naskah lontar Usadha Tiwang, yang telah ditransliterasi dari aksara Bali ke aksara Latin. Temuan: Hasil penelitian diketahui bahwa tiwang adalah penyakit yang mempunyai gejala badan terasa meluang, sakit dan ngilu, gelisah, mata mendelik, otot kaku bahkan sampai pingsan. Jenis tiwang dicirikan berdasarkan gejala yang muncul. Pengobatan dilaksanakan secara holistik oleh pengusada sesuai tatalaksana pengusada, dengan menggunakan ramuan obat-obatan yang terbuat dari campuran berbagai jenis tumbuh-tumbuhan atau bahan lainnya seperti arak, lengis tanusan, garam, gula, kapur, maupun santen, bahkan tain seksek serta iduh bang. Penggunaannya dengan cara dimakan, diminum, ditutuhkan, disemburkan, diuapkan atau dilulurkan, maupun ditempelkan. Takaran, cara pengolahan, serta cara pemakaian masih belum jelas. Implikasi: Masyarakat Bali tetap percaya terhadap sistim pengobatan tradisional Bali. Namun demikian, masyarakat Bali yang berobat ke tempat praktik pengobatan tradisional sangat sedikit. Simpulannya adalah pengobatan tradisional Bali dilakukan secara holistik untuk mencapai keseimbangan antara shtula sarira-suksma sarira-antahkarana sarira.
ABSTRAK<br />Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari kombinasi dua tanaman yaitu temu mangga (Curcuma mangga Val.) dan daun anting-anting (Acalypha indica L.) yang diolah dalam bentuk minuman serbuk instan.Hal ini dilakukan agar memudahkan dan praktis dalam penyajian serta memiliki waktu simpan yang lebih lama. Langkah awal yang dilakukan yaitu proses pembuatan serbuk instan melalui kristalisasi. Dari proses kristalisasi diperoleh jumalah serbuk instan temu mangga dan daun anting-anting sebanyak 840 gram. Pengujian aktivitas antibakteri menggunakan metode difusi sumur (modifikasi kirby Bauer). Dari hasil penelitian diperoleh bahwa konsentrasi serbuk instan menunjukkan adanya aktivitas antibakteri pada konsentrasi 80% dan 100% dengan daya hambat yang tergolong kuat sedangkan pada konsentrasi 60 % tergolong sedang dan pada konsentrasi 20% dan 40% tergolong lemah sebagai antibakteri.Peningkatan konsentrasi serbuk instan yang diberikan dari 20%, 40%, 60%, 80% dan 100% menunjukkan semakin besar diameter zona hambat yang terbentuk disekeliling sumur, karena semakin meningkatnya senyawa-senyawa berkhasiat dalam serbuk instan yang dapat menghambat pertumbuhan bakteri E.Coli.<br />Kata Kunci : aktivitas antibakteri, serbuk instan, Curcuma mangga Val, dan Acalypha indica L.<br />ABSTRACT<br />This study aims to determine the antibacterial activity of a combination of two plants, namely the meeting of mango (Curcuma mangga Val.) And earring leaves (Acalyphaindica L.) which are processed in the form of instant powder drinks. This is done to make it easy and practical in presentation and has a longer shelf time. The first step taken in the process of making instant powder through crystallization. During the crystallization process, there were 840 grams of instant powder meeting mango and earring leaves. Antibacterial activity testing using well diffusion method (modified by Bauer). The results showed that the concentration of instant powder showed antibacterial activity at concentrations of 80% and 100% with a relatively strong inhibitory power while at concentrations of 60% were classified as moderate and at concentrations of 20% and 40% were classified as weak as antibacterials. Increased concentrations of instant powder given from 20%, 40%, 60%, 80% and 100% indicate the larger diameter of inhibiting zones formed around the well, due to the increasing of efficacious compounds in instant powders that can inhibit the growth of E.Coli bacteria.<br />Keyword : antibacterial activities, instant powder, Curcuma mangga Val, Acalyphaindica L.
Traditional medication method in Bali use the Ayurveda principle known as Usadha. Usadha used herb or fruit as main component of medicine. One of them is Malaka fruit (Phyllanthus emblica L.) and commonly in Bali known as kalimaka, kalimoko, kamlika. Malaka can be processed through boiling using water and consumed as traditional drink (loloh). Malaka fruit has been known to contain vitamin C as antioxidant. Therefore, this research aims to determinant the antioxidant activity of malaka fruit loloh using DPPH (2,2-difenil-1-pikrillhidrazil). The result showed that malaka fruit loloh obtained was antioxidant activity with antioxidant capacity 164 mg/100 mL and IC50 691,1 µg/Ml. Further contains vitamin C obtained was 0,184 mg/100mL, Flavonoid was 3,15 mg/100mL, phenol was 375 mg/100mL and tannin was 546 mg/mL. Based on these result malaka fruit loloh can be use as on alternative for traditional medication.
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