We developed ac yclic amplification method for an organic afterglow nanoreporter for the real-time visualization of self-generated reactive oxygen species (ROS). We promoted semiconducting polymer nanoparticles (PFODBT) as acandidate for emitting near-infrared afterglow luminescence.I ntroduction of ac hemiluminescent substrate (CPPO) into PFODBT (PFODBT@CPPO) resulted in as ignificant enhancement of afterglow intensity through the dual cyclic amplification pathway involving singlet oxygen ( 1 O 2 ). 1 O 2 produced by PFODBT@CPPO induced cancer cell necrosis and promoted the release of damage-related molecular patterns,t hereby evoking immunogenic cell death (ICD)-associated immune responses through ROS-based oxidative stress. The afterglow luminescent signals of the nanoreporter were well correlated with light-driven 1 O 2 generation and anti-cancer efficiency.T his imaging strategy provides an on-invasive tool for predicting the therapeutic outcome that occurs during ROSmediated cancer therapy.

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The degradation mechanism of one new emerging pollutant ornidazole (ONZ) on TiO2 surface is explored using DFT calculations.

The adsorption characteristics and degradation mechanism of tinidazole on TiO2(101) and (001) surfaces under vacuum and aqueous solution conditions were studied by density functional theory (DFT).