Background: Both midline catheters (MCs) and peripherally inserted central catheters (PICCs) can cause venous thromboembolism (VTE), but the prevalence associated with each is controversial.Objective: To compare the risk of VTE between MCs and PICCs with a systematic review and meta-analysis. Methods:The Web of Science Core Collection, PubMed, Scopus, Embase, the Cochrane Library and ProQuest were searched from inception to January 2020. All studies comparing the risk of VTE between MCs and PICCs were included. Selected studies were assessed for methodological quality using the Downs and Black checklist. Two authors independently assessed the literature and extracted the data. Any different opinion was resolved through third-party consensus. Meta-analyses were conducted to generate estimates of VTE risk in patients with MCs versus PICCs, and publication bias was evaluated with RevMan 5.3. Results:A total of 86 studies were identified. Twelve studies were recruited, involving 40,871 patients. The prevalence of VTE with MCs and PICCs was 3.97% (310/7806) and 2.29% (758/33065), respectively. Meta-analysis showed that the prevalence of VTE with MCs was higher than that with PICCs (RR=1.53, 95% CI:1.33-1.76, p < .00001). Subgroup analyses by age showed that the prevalence of VTE with MCs was higher than that with PICCs in the adult group (RR=1.75, 95% CI: 1.38-2.22, p < .00001), and higher than that with PICCs in the other subgroups (RR=1.42, 95% CI: 1.19-1.69, p = .0001). Subgroup analyses by nation showed that the prevalence of VTE with MCs was higher than that with PICCs (RR=1.50, 95% CI: 1.30-1.73, p < .00001) in US subgroup and higher than that with PICCs (RR=2.87, 95% CI: 1.24-6.65, p = .01) in the other nations. The sensitivity analysis shows that the results from this meta-analysis are robust and all studies have no significant publication bias.

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ObjectiveSkill competence is essential for nursing students and experiential teaching method has become increasingly popular in China's nursing education. To systematically evaluate the effects of experiential teaching method on the development of nursing students’ skill competence, and to provide evidence for nursing education.MethodsThe China National Knowledge Infrastructure, VIP, Wanfang Data, PubMed, and Web of Science databases were searched from their inception until November 28, 2019. We screened the studies according to inclusion and exclusion criteria, extracted the data, and assessed the quality. Then, a meta-analysis was conducted.ResultsTotally 15 studies were included, and 1,633 nursing students were analyzed by Review Manager5.3 and Stata15.1 software. The results show that the experiential teaching method can significantly improve nursing students’ nursing skills such as training (SMD = 1.05, 95% CI: 0.95–1.16, P = 0.000), learning interest (ES = 0.93, 95% CI: 0.79–1.06), ability to analyze and solve problems (ES = 0.75, 95% CI: 0.55–0.94), ability to judge and innovative thinking (ES = 1.01, 95% CI: 0.77–1.25), abilities of understanding and perception (ES = 0.59, 95% CI: 0.34–0.83), and teaching satisfaction (ES = 1.26, 95% CI: 1.13–1.4).ConclusionsThe results suggest that the experiential teaching method is more effective for the nursing students’ skill competence than traditional teaching in China. However, due to the heterogeneity and bias risk, a large sample and high-quality studies are needed in future to confirm its effectiveness.

In order to explore the curative effect of early enteral nutrition nursing on patients with severe acute pancreatitis and the improvement of patients’ mental health and inflammation levels, this paper compares the curative effect of early enteral nutrition nursing and traditional care on patients with severe acute pancreatitis and the improvement effects of patients’ mental health and inflammation levels through controlled trials. Moreover, this paper combines statistical methods for data processing and visually expresses data through statistical graphs and statistical tables. Through the comparison of experiments, it can be seen that the improvement effect in all aspects of patients in the test group is significantly higher than that in the control group. Finally, through the analysis of the test results, it can be known that the use of early enteral nutrition nursing for patients with acute severe acute pancreatitis has a certain effect in improving their nutritional status, regulating immune function, and promoting mental health.