[3 + 2] annulations of spirocyclopropyl oxindoles with ynamides to offer biologically important spirocyclopenteneoxindoles in high yields with good diastereoselectivities were developed.
1,3-Cyclohexandione derived cyclic ketals and thiol ketals were used as O- and S-nucleophiles, respectively for the ring opening of donor-acceptor cyclopropanes catalyzed by Cu(OTf)2 and a series of functionalized alkylene...
A series of enantioenriched γ-hydroxybutyric acid derivatives were obtained via asymmetric ring-opening reactions of D–A cyclopropanes with 1,3-cyclodiones.
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