Cancer immunotherapy has achieved tremendous successful clinical results and obtained historic victories in tumor treatments. However, great limitations associated with feeble immune responses and serious adverse effects still cannot be neglected due to the complicated multifactorial etiology and pathologic microenvironment in tumors. The rapid development of nanomedical science and material science has facilitated the advanced progress of engineering biomaterials to tackle critical issues. The supramolecular biomaterials with flexible and modular structures have exhibited unparalleled advantages of high cargo-loading efficiency, excellent biocompatibility, and diversiform immunomodulatory activity, thereby providing a powerful weapon for cancer immunotherapy. In past decades, supramolecular biomaterials were extensively explored as versatile delivery platforms for immunotherapeutic agents or designed to interact with the key moleculars in immune system in a precise and controllable manner. In this review, we focused on the crucial role of supramolecular biomaterials in the modulation of pivotal steps during tumor immunotherapy, including antigen delivery and presentation, T lymphocyte activation, tumor-associated macrophage elimination and repolarization, and myeloid-derived suppressor cell depletion. Based on extensive research, we explored the current limitations and development prospects of supramolecular biomaterials in cancer immunotherapy.

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This study predicted the metabolic process of the residential building system in China toward 2050 by addressing the detailed provincial patterns and urban–rural disparity and the characterizing metabolisms of building materials in detail. The results show that after a rapid growth during 1980–1990, the in‐use stocks of residential buildings in China are expected to slow down in around 2030, reaching 75 billion m2 in 2050. Urban regions will account for 80% of total stocks, and provinces in the eastern and southern coastal areas will have the largest share. As demolition lags construction, the end‐of‐life residential buildings will continue to grow steadily with huge urban–rural and provincial differences, reaching 1.4 billion m2 by 2050. Regarding the metabolism of building materials, the inflow of most materials will decrease after 2030, while the outflow will increase steadily toward inflow. Based on the recycling outlook of construction and demolition waste and the corresponding environmental benefit, it is indicated that under the Chinese government's ambitious planning and vigorous promotion, prior to the middle of the century, the building system has the potential to transition to a sustainable future that meets residents’ housing needs with a remarkable decreasing input of raw materials thereby notably decreasing pressures on the environment, which will significantly benefit the goal of carbon neutrality in China.