Background The long-term pulmonary function and related physiological characteristics of COVID-19 survivors have not been studied in depth, thus many aspects are not understood. Methods COVID-19 survivors were recruited for high resolution computed tomography (HRCT) of the thorax, lung function and serum levels of SARS-CoV-2 IgG antibody tests 3 months after discharge. The relationship between the clinical characteristics and the pulmonary function or CT scores were investigated. Findings Fifty-five recovered patients participated in this study. SARS-CoV-2 infection related symptoms were detected in 35 of them and different degrees of radiological abnormalities were detected in 39 patients. Urea nitrogen concentration at admission was associated with the presence of CT abnormalities ( P = 0.046, OR 7.149, 95% CI 1.038 to 49.216). Lung function abnormalities were detected in 14 patients and the measurement of D-dimer levels at admission may be useful for prediction of impaired diffusion defect ( P = 0.031, OR 1.066, 95% CI 1.006 to 1.129). Of all the subjects, 47 of 55 patients tested positive for SARS-CoV-2 IgG in serum, among which the generation of Immunoglobulin G (IgG) antibody in female patients was stronger than male patients in infection rehabilitation phase. Interpretation Radiological and physiological abnormalities were still found in a considerable proportion of COVID-19 survivors without critical cases 3 months after discharge. Higher level of D-dimer on admission could effectively predict impaired DLCO after 3 months discharge. It is necessary to follow up the COVID-19 patients to appropriately manage any persistent or emerging long-term sequelae. Funding Key Scientific Research Projects of Henan Higher Education Institutions

No abstract

No abstract

Although mixed use is an emerging strategy that has been widely accepted in urban planning for promoting neighbourhood vibrancy, there is no consensus on how to quantitatively measure the mix and the effects of mixed use on neighbourhood vibrancy. Shannon entropy, the most commonly used diversity measurement in assessing mixed use, has been found to be inadequate in measuring the multifaceted, multidimensional characteristics of mixed use. And lack of data also makes it difficult to find the relationship between mixed use and neighbourhood vibrancy. However, the recent availability of new sources including mobile phone data and Point of Interest (POI) data have made it possible to develop new indices of mixed use and neighbourhood vibrancy to analyse their relationships. Taking advantage of these emerging new data sources, this study used the numbers of mobile phone users in a 24-hour period as a proxy of neighbourhood vibrancy and used POIs from a navigation database to develop a series of mixed-use indicators that can better reflect the multifaceted, multidimensional characteristics of mixed-use neighbourhoods. The Hill numbers, a unified form of diversity measurement used in ecological literature that includes richness, entropy, and the Simpson index, are used to measure the degrees of mixed use. Using such fine-grained data sets and the Hill numbers allowed us to obtain better insights into the relationship between mixed use and neighbourhood vibrancy. Four models varying in POI measurements that reflect different dimensions of mixed use were presented. The results showed that either POI density or entropy can explain approximately 1% of neighbourhood vibrancy, while POI richness contributes significantly in improving neighbourhood vibrancy. The results also revealed that the entropy has limitations as a measure for representing mixed use and demonstrated the necessity of adopting a set of more appropriate measurements for mixed use. Increasing the number of POIs has limited power to improve neighbourhood vibrancy compared with encouraging the mixing of complementary POIs. These exploratory findings may be useful for adjusting mixeduse assessments and to help guide urban planning and neighbourhood design.ARTICLE HISTORY