In the past few years, we have witnessed rapid development of autonomous driving. However, achieving full autonomy remains a daunting task due to the complex and dynamic driving environment. As a result, self-driving cars are equipped with a suite of sensors to conduct robust and accurate environment perception. As the number and type of sensors keep increasing, combining them for better perception is becoming a natural trend. So far, there has been no indepth review that focuses on multi-sensor fusion based perception. To bridge this gap and motivate future research, this survey devotes to review recent fusion-based *equal contribution
Background
Ultraviolet (UV) is a common stressor of skin and repeated UVA radiation contributes to photoaging. (–)-Epigallocatechin-3-Gallate (EGCG), as the major polyphenol that is found in green tea, and catechins and have shown considerable antioxidant capacity.
Purpose
Our study aims to explore the effects of EGCG on UVA-induced skin photoaging process and associated mechanisms.
Methods
In this study, human skin fibroblasts (HSFs) were treated with UVA and EGCG, and subsequent changes in cell morphology, telomeres, antioxidant capacity, cell cycle, and related genes were evaluated to examine the role and mechanisms of EGCG in delaying skin photoaging.
Results
HSF exposed to UVA underwent an increase in aging-related biomarkers and telomere shortening. Also, UVA radiation inhibited the secretion of transforming growth factor-beta1 (TGF-β1), induced cell cycle arrest, down-regulated antioxidant enzymes, and promoted the accumulation of oxidative product malondialdehyde (MDA) to cause further damage to cells. Increased expression of matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinase-1 (TIMP-1), p66 at mRNA levels were also observed after UVA irradiation. EGCG treatment effectively inhibited above damage processes caused by UVA radiation in HSF.
Conclusion
Our study indicated that the potential mechanism of EGCG retarding photoaging is closely related to its powerful antioxidant effects and the ability to regulate the expression of related genes, and the usage of EGCG will be a potential strategy in preventing skin photoaging induced by UVA radiation.
It has been well recognized that fusing the complementary information from depth-aware LiDAR point clouds and semantic-rich stereo images would benefit 3D object detection. Nevertheless, it is not trivial to explore the inherently unnatural interaction between sparse 3D points and dense 2D pixels. To ease this difficulty, the recent proposals generally project the 3D points onto the 2D image plane to sample the image data and then aggregate the data at the points. However, this approach often suffers from the mismatch between the resolution of point clouds and RGB images, leading to sub-optimal performance. Specifically, taking the sparse points as the multi-modal data aggregation locations causes severe information loss for highresolution images, which in turn undermines the effectiveness of multi-sensor fusion. In this paper, we present VPFNet-a new architecture that cleverly aligns and aggregates the point cloud and image data at the 'virtual' points. Particularly, with their density lying between that of the 3D points and 2D pixels, the virtual points can nicely bridge the resolution gap between the two sensors, and thus preserve more information for processing. Moreover, we also investigate the data augmentation techniques that can be applied to both point clouds and RGB images, as the data augmentation has made non-negligible contribution towards 3D object detectors to date. We have conducted extensive experiments on KITTI dataset, and have observed good performance compared to the state-of-the-art methods. Remarkably, our VPFNet achieves 83.21% moderate 3D AP and 91.86% moderate BEV AP on the KITTI test set, ranking the 1st since May 21th, 2021. The network design also takes computation efficiency into consideration -we can achieve a FPS of 15 on a single NVIDIA RTX 2080Ti GPU. The code will be made available for reproduction and further investigation.
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