The clinical efficacy of an oral contraceptive containing 0.150 mg desogestrel + 0.030 mg ethinylestradiol was studied by nine Scandinavian investigators in a total of 198 women and 2055 cycles. The preparation was found to be highly effective, and a low incidence of minor adverse side effects was reported. The incidence of spotting and breakthrough bleeding, though initially rather high, decreased over the first six cycles, and coincided with a high incidence of missed tablets. No serious side effects occurred, and there were few withdrawals because of complaints suspected of being attributable to the preparation.
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