The current study describes a simple, rapid and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using Excoecaria agallocha (E. agallocha) leaf extract as stabilizer, bioreductant and capping agent. Synthesized AgNPs were characterized by UV-Visible spectroscopy (UV-Vis), X-ray diffraction (XRD), fourier transform infrared (FT-IR) spectroscopy, field emission scanning electron microscopy (FESEM) and energy dispersive X-ray spectroscopy (EDX). Generation of AgNPs was initially confirmed with the color change from yellow to dark brown which produces intense absorbance spectra at 440 nm in UV-Vis spectroscopy without any shifting of peaks. Further, XRD pattern confirms that the synthesized AgNPs was face centered cubic (fcc) crystalline in structure with an average size of 20 nm. On the other hand, FTIR spectrum reveals that the active metabolites like water soluble phenolic compounds, flavonoids, methylene groups, amides and carboxylate groups. These active biocompounds plays a vital role in the reduction of Ag ? into their nanoscale values, it also acts as a stabilizing and surface functionalization agent. FESEM micrographs of synthesized AgNPs shows spherical and hexagonal shaped well dispersed particles in the dimension ranging between 23 and 42 nm. EDAX confirms the presence of silver (Ag) as the major constituent element without any impurities; also substantiate the stability of generated AgNPs. The biomedical insights of nanoparticles (NPs) were assessed through radical scavenging and antibacterial properties. Additionally, synthesized AgNPs was also exhibits an excellent cytotoxic effect against human breast carcinoma cell lines (MCF-7). This study proves that synthesized AgNPs can be developed as a potential nano-drug formulation to combat pathogenic disease and also for the expansion of breast cancer therapy.

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The present investigation was aimed to synthesis of silver nanoparticles (AgNPs) using Mallotus philippensis leaf extract and their antibacterial potential against Bacillus cereus isolated from HIV positive patient. In this, UV-Visible spectroscopy showed the high peak of absorption band at 450 nm. Based on XRD analysis, face centered cubic structure and average size of the AgNPs was around 16 nm. FTIR spectroscopy study revealed the seventeen functional groups of the AgNPs was observed. The morphology of AgNPs was spherical, oval shapes and diameter of the particle size ranges between 9 and 24 nm was measured using transmission electron microscopy (TEM). In addition to these green synthesized AgNPs were found to express the higher efficacy in inhibiting the growth of Bacillus cereus (B. cereus) isolated from the HIV-positive patient.

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