In this article, we traced the development of fauna, bioecology and populations of more than 50 species of the main family Lepidoptera, found in the biocenosis of Uzbekistan. Research has been conducted in agricultural crops, forestry and natural biocenoses, and representatives of the Lepidoptera family have been involved in scientific research on species that cause great economic damage. Trichogrammatidae, Braconidae, Ichneumonidae, Chalcididae, Pteromalidae, and Tachinidae, the main entomophagous species that effectively control the number of members of the Lepidoptera family, have also been identified and systematically analyzed. The representatives of the family Trichogrammatidae, which are effective parasitic entomophagous in the management of the number of representatives of the family Lepidoptera. The study revealed that in the agrobiocenoses of cotton, mung bean, corn and cabbage in Tashkent province, the level of occurrence of three main species of nightshade pests of the family Trichogrammatidae, which are egg parasites of the family Lepidoptera, was determined. This means that the number of nights can be effectively controlled by members of the trichogramma family.