We have carried out a study of the tissular tropism of the strain Y of T. cruzi considering that the different strains of T. cruzi show a great instability in their pathogenic properties with the aim of proving that the classifications of his parasite based in its tissular tropism are not reliable given that these characteristics are subject to change as can be seen by comparing our results with those of other authors.In our study, the Y. strain of T. cruzi shows a strong pancytotropic action, specially with marked cardiotropic aspects. The lack of affectation in the lymphatic ganglion and the small proportion of spleen lesions (8 %) as well as the absence of pseudocysts at this level is surprising in a strain which was described as emi nently reticulotropic. Our data show that this strain produces car diac pseudocysts without lesions of the parasitized muscle fiber.The above mentioned data evidence that the biological beha vior of a strain and specially its tissular tropism are susceptible to present variations with time.R ésumé : Cardiopathie chagasique aiguë dans un modèle expérimental produit par une souche de T. cruzi (type 1).
Étude du tropisme tissulaire de la souche Y de T. cruzi et compa raison des résultats avec les données des autres auteurs.La souche Y présente un grand pancytotropisme avec un car diotropisme très marqué. L'absence de localisation ganglionnaire, le fait qu'il y a seulement 8 % de lésions spléniques, l'absence de pseudokystes à ce niveau sont inattendus, pour une souche qui a été décrite comme éminemment réticulotropique.Nos données montrent que cette souche produit des pseudokystes dans le coeur sans lésions de la cellule parasitée. Les données men tionnées prouvent que le comportement biologique et spécialement son tropisme tissulaire peuvent changer avec le temps.
RÉSUMÉ. Une étude morphométrique comparative a été réalisée dans une infection expéri mentale avec Trypanosoma b. brucei en utilisant deux méthodes morphométriques, l'une conven tionnelle (microscopique) et l 'autre au moyen d'un ordinateur IBAS-1. La souche de T. b. brucei utilisée a été maintenue pendant 10 ans en laboratoire par des passages mécaniques de souris à souris.L'administration d'une dose réduite de suramine agit sur le nombre des formes rencontrées. Les résultats des études morphométriques varient selon la technique utilisée. La présence des formes postéronucléaires, multinucléaires et « stumpy » en division a été confirmée pour notre souche et l'administration de doses réduites de suramine a augmenté de manière considérable le nombre de ces formes.
Mots-clés
SUMMARY.A comparative morphometrical study of the experimental infection with T. b. brucei was realized using the conventional method and the IBAS-1 analytic computer.The studied strain of T. b. brucei was preserved during 10 years in laboratory conditions, through inoculations from mice to mice.The effect of a low dose of suramin upon the percentage of different morphological forms of the parasite was analysed and compared with the untreated lots.Certain differences could be appreciated in the results of the two methods of morphometrical studies.The presence of posteronuclear, multinuclear and « stumpy » dividing forms was confirmed in our study.The administration of low doses of suramin produces a serious increase of the number of the dividing, multinuclear and « stumpy » forms.
The emergence of sustainability in business has led to a growing number of market players becoming concerned about ESG rating, which includes environmental, social and governance aspects. Investors are also pricing in the scores generated by ESG indicators. The growing interest in ESG data raises the question of the reliability of the scores provided by different ESG rating agencies. This research explores the differences in the methodologies used by the most reputable ESG rating agencies through a content analysis. The inconsistency of ESG scores will be investigated by taking a random sample of companies in eight pre-selected industries and subjecting them to a correlation test. The purpose of this is to highlight the uncertainties associated with ESG ratings and to draw attention to the fact that ensuring the reliability, consistency, and transparency of ESG information remains an unresolved issue and challenge for both decision makers and users.
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