No abstract

This study lends support to others indicating the apparent safety and effectiveness of multiple transcervical insertions of quinacrine hydrochloride as pellets in 240 mg dosage to achieve permanent sterilization. In order to study the effects of the number of quinacrine pellet insertions and the site of placement of the pellets in the uterus of prehysterectomy volunteers, a scoring system of histological changes in the Fallopian tube was designed. Quinacrine pellets were deposited at the fundus using a straight inserter in 16 women, and at the cornua using a curved inserter in 17 women. Each group had at least five women receiving one, two or three insertions at one-week intervals. Results indicate that neither the number of insertions nor the place of deposition of the pellets affects the degree of tubal inflammation and fibrosis.

A new copper intrauterine device is described. Experience during 40 000 woman-months of use indicates that there have been no pregnancies and only 0.4 expulsions. At the end of 30 months of follow-up, 87.5% of the women are still wearing the device.

A simple, safe and accurate method of localizing placenta by ultrasound is described. The accuracy of this technique is verified by anatomical comparison with the standara procedures. A method is suggested for diagrammatically charting the data collected on Doppler placentography. The study revealed that the ultrasonic Dopplei technique has a uniform reliability of 88.5% in experienced hands. The technique has specific advantages, particularly its simplicity and reproducibility which is superior to most available methods that are more sophisticated and hazardous.